ID Y009_CHLTE Reviewed; 483 AA.
AC Q8KGF9;
DT 19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 01-MAY-2013, entry version 60.
DE RecName: Full=Uncharacterized RNA methyltransferase CT0009;
DE EC=2.1.1.-;
GN OrderedLocusNames=CT0009;
OS Chlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS).
OC Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC Chlorobaculum.
OX NCBI_TaxID=194439;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49652 / DSM 12025 / TLS;
RX PubMed=12093901; DOI=10.1073/pnas.132181499;
RA Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M.,
RA Dodson R.J., DeBoy R.T., Gwinn M.L., Nelson W.C., Haft D.H.,
RA Hickey E.K., Peterson J.D., Durkin A.S., Kolonay J.F., Yang F.,
RA Holt I.E., Umayam L.A., Mason T.M., Brenner M., Shea T.P.,
RA Parksey D.S., Nierman W.C., Feldblyum T.V., Hansen C.L., Craven M.B.,
RA Radune D., Vamathevan J.J., Khouri H.M., White O., Gruber T.M.,
RA Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A., Fraser C.M.;
RT "The complete genome sequence of Chlorobium tepidum TLS, a
RT photosynthetic, anaerobic, green-sulfur bacterium.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RNA M5U
CC methyltransferase family.
CC -!- SIMILARITY: Contains 1 TRAM domain.
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DR EMBL; AE006470; AAM71257.1; -; Genomic_DNA.
DR RefSeq; NP_660915.1; NC_002932.3.
DR ProteinModelPortal; Q8KGF9; -.
DR STRING; 194439.CT0009; -.
DR DNASU; 1006160; -.
DR EnsemblBacteria; AAM71257; AAM71257; CT0009.
DR GeneID; 1006160; -.
DR KEGG; cte:CT0009; -.
DR PATRIC; 21398119; VBIChlTep116050_0009.
DR eggNOG; COG2265; -.
DR HOGENOM; HOG000029870; -.
DR KO; K03215; -.
DR OMA; LNGLNNC; -.
DR ProtClustDB; CLSK637102; -.
DR BioCyc; CTEP194439:GHN0-10-MONOMER; -.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0001510; P:RNA methylation; IEA:GOC.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR Gene3D; 2.40.50.140; -; 1.
DR InterPro; IPR001566; 23S_rRNA_MeTrfase_RlmD.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR002792; TRAM_dom.
DR InterPro; IPR010280; U5_MeTrfase.
DR Pfam; PF01938; TRAM; 1.
DR Pfam; PF05958; tRNA_U5-meth_tr; 1.
DR SUPFAM; SSF50249; Nucleic_acid_OB; 1.
DR TIGRFAMs; TIGR00479; rumA; 1.
DR PROSITE; PS50926; TRAM; 1.
DR PROSITE; PS01230; TRMA_1; 1.
DR PROSITE; PS01231; TRMA_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S; Complete proteome; Iron; Iron-sulfur; Metal-binding;
KW Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW Transferase.
FT CHAIN 1 483 Uncharacterized RNA methyltransferase
FT CT0009.
FT /FTId=PRO_0000161966.
FT DOMAIN 11 71 TRAM.
FT ACT_SITE 439 439 Nucleophile (By similarity).
FT METAL 84 84 Iron-sulfur (4Fe-4S) (By similarity).
FT METAL 90 90 Iron-sulfur (4Fe-4S) (By similarity).
FT METAL 93 93 Iron-sulfur (4Fe-4S) (By similarity).
FT METAL 187 187 Iron-sulfur (4Fe-4S) (By similarity).
FT BINDING 312 312 S-adenosyl-L-methionine (By similarity).
FT BINDING 341 341 S-adenosyl-L-methionine; via carbonyl
FT oxygen (By similarity).
FT BINDING 362 362 S-adenosyl-L-methionine (By similarity).
FT BINDING 412 412 S-adenosyl-L-methionine (By similarity).
SQ SEQUENCE 483 AA; 54475 MW; ADA9D915A6EFEAD5 CRC64;
MHTPLEQQEI RYRKGDIIEL TITDHAEKDK CFGKTTEGMG VMVSGILAPG DRVSAQIYKV
KSRYLEARAI EVLEASPDRV EPVCPVFGSC GGCKWMHVSY EAQLRYKHKK VTDSLEHIGG
FESPDVRPVL AAPDALHYRN KVEFSCSNMR YLLQSEIDSD QLAKPKTFAL GFHAPGNFEK
VLDLDTCYLA KECMNRVLNV LRDFAIERGL EPYAAKAHEG YLRNLMLRYS ERHEQLMVNI
VTSWYDKALM QALKERLEAA MPEQQMTLLN NVTTRKNTVA TGEQEYVISG DGYVTERLGD
LDFRISANSF FQTNTRQAET LYDQIIAVGG ITPEDTVYDL YCGTGTITLY LARHCKQAIG
IEVVESAVKD AEMNAELNGL SNTVFFQADL KNFHAMQEAL EPYAKPRIIV TDPPRAGMHP
KALDTMLKLQ PERIVYVSCN PDNLARDGKE IAARGYRMTS AQPVDMFPQT NHIETVACFE
RAE
//
