ID Q8KHI7_SHIDY Unreviewed; 306 AA.
AC Q8KHI7;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=IpaB {ECO:0000313|EMBL:AAM89549.1};
DE Flags: Fragment;
GN Name=ipaB {ECO:0000313|EMBL:AAM89549.1};
OS Shigella dysenteriae.
OG Plasmid virulence plasmid {ECO:0000313|EMBL:AAM89549.1}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=622 {ECO:0000313|EMBL:AAM89549.1};
RN [1] {ECO:0000313|EMBL:AAM89549.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SD0253 {ECO:0000313|EMBL:AAM89551.1}, and SD0497
RC {ECO:0000313|EMBL:AAM89549.1};
RC PLASMID=virulence plasmid {ECO:0000313|EMBL:AAM89549.1};
RX PubMed=14562958; DOI=10.1007/s00239-003-2460-3;
RA Escobar-Paramo P., Giudicelli C., Parsot C., Denamur E.;
RT "The evolutionary history of Shigella and enteroinvasive Escherichia coli
RT revised.";
RL J. Mol. Evol. 57:140-148(2003).
CC -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000256|ARBA:ARBA00004301};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004301}. Secreted
CC {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the SctE/SipB/YopB family.
CC {ECO:0000256|ARBA:ARBA00035640}.
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DR EMBL; AF330464; AAM89549.1; -; Genomic_DNA.
DR EMBL; AF330466; AAM89551.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8KHI7; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 2.
DR InterPro; IPR006972; BipB-like_C.
DR InterPro; IPR032391; IpaB/BipB/SctE_N.
DR InterPro; IPR003895; T3SS_SctE/BipB.
DR Pfam; PF04888; SseC; 1.
DR Pfam; PF16535; T3SSipB; 1.
DR PRINTS; PR01375; BACINVASINB.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Host membrane {ECO:0000256|ARBA:ARBA00022870};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Plasmid {ECO:0000313|EMBL:AAM89549.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT DOMAIN 76..231
FT /note="IpaB/BipB/SctE N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16535"
FT DOMAIN 252..305
FT /note="Translocator protein BipB-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04888"
FT REGION 280..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 127..164
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 281..306
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 306
FT /evidence="ECO:0000313|EMBL:AAM89549.1"
SQ SEQUENCE 306 AA; 34042 MW; 9BC0590414BE692F CRC64;
MHNVSTTTTG LPLAKILAST ELGDNTIQAA NDAANKLFSL TIADLTANKN INTTNAHSTS
NILIPELKAP KSLNASSQLT LLIGNLIQIL GEKSLTALTN KITAWKSQQQ ARQQKNLEFS
DKINTLLSET EGLTRDYEKQ INKLKNADSK IKDLENKINQ IQTKLSELDP DSPENKKLRR
EEIQLTIKKD AAVKDRTLIE QKTLSIHSKL TDKSMQLEKE IDSFSAFSNT ASAEQLSTQQ
KSLTGLASVT QLMATFIQLV GKNNEESLKN DLALFQSLQE SRKTEMERKS DEYAAEVRKA
EELNRV
//
