ID APT2_RHIEC Reviewed; 184 AA.
AC Q8KKS1;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 2.
DT 01-MAY-2013, entry version 67.
DE RecName: Full=Adenine phosphoribosyltransferase 2;
DE Short=APRT 2;
DE EC=2.4.2.7;
GN Name=apt2; OrderedLocusNames=RHE_PD00341;
OS Rhizobium etli (strain CFN 42 / ATCC 51251).
OG Plasmid sym p42d.
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=347834;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFN 42 / ATCC 51251;
RX PubMed=12801410; DOI=10.1186/gb-2003-4-6-r36;
RA Gonzalez V., Bustos P., Ramirez-Romero M.A., Medrano-Soto A.,
RA Salgado H., Hernandez-Gonzalez I., Hernandez-Celis J.C., Quintero V.,
RA Moreno-Hagelsieb G., Girard L., Rodriguez O., Flores M.,
RA Cevallos M.A., Collado-Vides J., Romero D., Davila G.;
RT "The mosaic structure of the symbiotic plasmid of Rhizobium etli CFN42
RT and its relation to other symbiotic genome compartments.";
RL Genome Biol. 4:R36.1-R36.13(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFN 42 / ATCC 51251;
RX PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT "The partitioned Rhizobium etli genome: genetic and metabolic
RT redundancy in seven interacting replicons.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
CC -!- FUNCTION: Catalyzes a salvage reaction resulting in the formation
CC of AMP, that is energically less costly than de novo synthesis (By
CC similarity).
CC -!- CATALYTIC ACTIVITY: AMP + diphosphate = adenine + 5-phospho-alpha-
CC D-ribose 1-diphosphate.
CC -!- PATHWAY: Purine metabolism; AMP biosynthesis via salvage pathway;
CC AMP from adenine: step 1/1.
CC -!- SUBUNIT: Homodimer (By similarity).
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the purine/pyrimidine
CC phosphoribosyltransferase family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; U80928; AAM55053.2; -; Genomic_DNA.
DR RefSeq; NP_660052.2; NC_004041.2.
DR HSSP; P07741; 1ZN8.
DR ProteinModelPortal; Q8KKS1; -.
DR STRING; 347834.RHE_PD00341; -.
DR EnsemblBacteria; AAM55053; AAM55053; RHE_PD00341.
DR GeneID; 1005231; -.
DR KEGG; ret:RHE_PD00341; -.
DR PATRIC; 23081243; VBIRhiEtl108884_0314.
DR eggNOG; COG0503; -.
DR HOGENOM; HOG000036776; -.
DR KO; K00759; -.
DR OMA; APVISAM; -.
DR ProtClustDB; PRK02304; -.
DR BioCyc; RETL347834:GJJ0-5567-MONOMER; -.
DR UniPathway; UPA00588; UER00646.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003999; F:adenine phosphoribosyltransferase activity; IEA:HAMAP.
DR GO; GO:0006168; P:adenine salvage; IEA:HAMAP.
DR GO; GO:0044209; P:AMP salvage; IEA:UniProtKB-UniPathway.
DR GO; GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
DR HAMAP; MF_00004; Aden_phosphoribosyltr; 1; -.
DR InterPro; IPR005764; Ade_phspho_trans.
DR InterPro; IPR000836; PRibTrfase_dom.
DR Pfam; PF00156; Pribosyltran; 1.
DR PROSITE; PS00103; PUR_PYR_PR_TRANSFER; FALSE_NEG.
PE 3: Inferred from homology;
KW Complete proteome; Cytoplasm; Glycosyltransferase; Plasmid;
KW Purine salvage; Transferase.
FT CHAIN 1 184 Adenine phosphoribosyltransferase 2.
FT /FTId=PRO_0000334716.
SQ SEQUENCE 184 AA; 19027 MW; 9B715686CDB75F91 CRC64;
MIVAVPNSGA SRINQSGVEA LREFPNFPIG GILFKDIAPM LAGRGALGEV VSTVASQVSG
TEIDAILAVD ARGFILGASL ADRLGCGFIM VRKPGKLPGD VLSFEYSCEY CSGTLEVTAG
LIGDGLRCLI ADDLLATGGT ARATGNFVKS QGGEIAGYAF ILEIEVLKGR RQLDDAPVIS
AMTC
//
