ID Q8KU24_ECOLX Unreviewed; 408 AA.
AC Q8KU24;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=IbrA {ECO:0000313|EMBL:AAM53133.1};
DE SubName: Full=Phosphoadenosine phosphosulfate reductase {ECO:0000313|EMBL:EAB7204796.1};
GN Name=ibrA {ECO:0000313|EMBL:AAM53133.1};
GN ORFNames=D4U49_20060 {ECO:0000313|EMBL:EAB7204796.1}, FV293_24620
GN {ECO:0000313|EMBL:TXQ29451.1}, FVB16_02645
GN {ECO:0000313|EMBL:MPU47772.1}, G3W53_22765
GN {ECO:0000313|EMBL:NEN72878.1}, HX136_12760
GN {ECO:0000313|EMBL:QLG57649.1};
OS Escherichia coli.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562 {ECO:0000313|EMBL:AAM53133.1};
RN [1] {ECO:0000313|EMBL:AAM53133.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ECOR-9 {ECO:0000313|EMBL:AAM53133.1};
RX PubMed=12057959; DOI=10.1128/JB.184.13.3640-3648.2002;
RA Sandt C.H., Hopper J.E., Hill C.W.;
RT "Activation of prophage eib genes for immunoglobulin-binding proteins by
RT genes from the IbrAB genetic island of Escherichia coli ECOR-9.";
RL J. Bacteriol. 184:3640-3648(2002).
RN [2] {ECO:0000313|EMBL:EAB7204796.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=587367 {ECO:0000313|EMBL:EAB7204796.1};
RA Ashton P.M., Dallman T., Nair S., De Pinna E., Peters T., Grant K.;
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:MPU47772.1, ECO:0000313|Proteomes:UP000392867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WU2356 {ECO:0000313|EMBL:MPU47772.1,
RC ECO:0000313|Proteomes:UP000392867};
RA Neumann N.;
RT "Identification of Water Treatment Resistant and Multidrug Resistant
RT Urinary Pathogenic Escherichia coli in Wastewater.";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:TXQ29451.1, ECO:0000313|Proteomes:UP000321295}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1_45_11 {ECO:0000313|EMBL:TXQ29451.1,
RC ECO:0000313|Proteomes:UP000321295};
RA Siniagina M.N., Markelova M.I., Laikov A.V., Boulygina E.A.,
RA Khusnutdinova D.R., Kharchenko A., Grigoryeva T.V.;
RT "Whole genome analysis of cultivated E. coli strains isolated from CD
RT patients and healthy donors.";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:QLG57649.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EC2 {ECO:0000313|EMBL:QLG57649.1};
RX PubMed=32739475;
RA Mowlaboccus S., Daley D., Pang S., Gottlieb T., Merlino J., Nimmo G.R.,
RA George N., Korman T.M., Streitberg R., Robson J., Peachey G., Collignon P.,
RA Bradbury S., Colombi E., Ramsay J.P., Rogers B.A., Coombs G.W.;
RT "Identification and characterisation of fosfomycin resistance in
RT Escherichia coli urinary tract infection isolates from Australia.";
RL Int. J. Antimicrob. Agents 56:0-106121(2020).
RN [6] {ECO:0000313|EMBL:NEN72878.1, ECO:0000313|Proteomes:UP000471360}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=8375wB1 {ECO:0000313|EMBL:NEN72878.1,
RC ECO:0000313|Proteomes:UP000471360};
RA Subbiah M., Call D.;
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|Proteomes:UP000509796}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC2 {ECO:0000313|Proteomes:UP000509796};
RA Mowlaboccus S., Daley D., Pang S., Gottlieb T., Nimmo G.R., George N.,
RA Korman T.M., Strietberg R., Robson J., Peachey G., Collignon P.,
RA Bradbury S., Colombi E., Ramsay J.P., Rogers B.A., Coombs G.W.;
RT "Identification and Characterisation of Fosfomycin Resistance in
RT Escherichia coli Urinary Tract Infection Isolates from Australia.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AF460182; AAM53133.1; -; Genomic_DNA.
DR EMBL; AAAFOP010000071; EAB7204796.1; -; Genomic_DNA.
DR EMBL; VOTT01000014; MPU47772.1; -; Genomic_DNA.
DR EMBL; JAAGYP010000047; NEN72878.1; -; Genomic_DNA.
DR EMBL; CP058571; QLG57649.1; -; Genomic_DNA.
DR EMBL; VRXD01000053; TXQ29451.1; -; Genomic_DNA.
DR RefSeq; WP_001145450.1; NZ_WSIO01000082.1.
DR PATRIC; fig|562.7964.peg.4305; -.
DR Proteomes; UP000321295; Unassembled WGS sequence.
DR Proteomes; UP000392867; Unassembled WGS sequence.
DR Proteomes; UP000471360; Unassembled WGS sequence.
DR Proteomes; UP000509796; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd01713; PAPS_reductase; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR021845; DUF3440.
DR InterPro; IPR002500; PAPS_reduct.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR30083:SF0; 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SULFOTRANSFERASE (PAPS REDUCTASE)_FAD SYNTHETASE-RELATED; 1.
DR PANTHER; PTHR30083; UNCHARACTERIZED; 1.
DR Pfam; PF11922; DUF3440; 2.
DR Pfam; PF01507; PAPS_reduct; 2.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 4: Predicted;
FT DOMAIN 32..85
FT /note="Phosphoadenosine phosphosulphate reductase"
FT /evidence="ECO:0000259|Pfam:PF01507"
FT DOMAIN 163..238
FT /note="Phosphoadenosine phosphosulphate reductase"
FT /evidence="ECO:0000259|Pfam:PF01507"
SQ SEQUENCE 408 AA; 48446 MW; F7BAF03E3430DBFB CRC64;
MPVTITKIRT GEDVLSAAIH RIEWLFETFS SVCLSFSGGK DSTVLFHLVA EVAYRKKRRF
SVLFIDWEAQ YQCTIDHIQK MRMMYQDVTD TFYWVALPLT TVNGVSQFQP EWICWEPGVE
WVRQPPEDAI TDMAYFPFYR YAMTFEEFVP AFSSWFASNQ CSVAILTGVR ADESLNRFMG
LVSQRKLRYA DDKPWTTASP EGFYYTMYPL YDWKTNDIWV YNAKTCAIYN PLYDLMYRAG
IPLRNMRVCE PFGPEQRKGL WLYHVLEPET WARMCERVSG AASGALYANE SGAYFALRKR
MSKPSHHTWR SYAFFLLDVM PERTAEHYRN KIAVYLRWYQ NRGFPDDIPD EQENDLGCRD
VPSWRRICKT LIKNDFWCRT LSFSPNKPRH YERYLQRMNE RRKEWGIL
//
