ID Q8LLA9_HORVU Unreviewed; 963 AA.
AC Q8LLA9;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE SubName: Full=RGH1A {ECO:0000313|EMBL:AAM22828.1};
GN Name=RGH1a {ECO:0000313|EMBL:AAM22828.1};
OS Hordeum vulgare (Barley).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX NCBI_TaxID=4513 {ECO:0000313|EMBL:AAM22828.1};
RN [1] {ECO:0000313|EMBL:AAM22828.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12172030; DOI=10.1105/tpc.002238;
RA Wei F., Wing R.A., Wise R.P.;
RT "Genome dynamics and evolution of the Mla (powdery mildew) resistance locus
RT in barley.";
RL Plant Cell 14:1903-1917(2002).
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; AF427791; AAM22828.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8LLA9; -.
DR SMR; Q8LLA9; -.
DR ExpressionAtlas; Q8LLA9; baseline and differential.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1116; OS11G0657900 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT DOMAIN 7..91
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 196..424
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 963 AA; 109211 MW; 1E18FA6CAB7A3B03 CRC64;
MHVVTGAMGS LLPKLGQLLM EEYKLHKRVK NDVEFLRKEL ESMHTALIKV GEVPRHQLDK
QVKLWADEVR DLSYNMEDVV DKFLVRVDGV DPHDNTDRFK GIMRKMIGLF KKGKNHHQIA
DAIKEIKEQL QEVAARRDRN KVEGIASNPM EAIPIDPCLR ALYAEATELV GIYGKRDEDI
MRLLSMEGED DASNKRLKKV SIVGFGGLGK TTLAKAVYEN IKGDFDCRAF VPVGQNPDMK
KVFRDILIDL RVSNSELAEL DERQLINKLH EFLENKRYLV IIDDIWDAKL WERINFAFSN
RNNLGSRLII TTRIFSVSKS SCMLPDDAVY EMKPLSDDDS RSLFYKRIFP SESGCPNEFE
QVSEDILKKC GGVPLAIITI ASSLASGQKV KPKSEWDILL QSLGSGLTKD NSLEEMRRIL
SFSYYDLPDH LKTCLLYLCI YPEDSMIDRD RLIWKWVAEG FIHQGNQGTS LFLLGLNYFN
QLINRSMIQP IYDGLGEVSA CRVHDMVLDL ICNLSHEAKF VNVLNGTRDS MSSQSNVRRL
SLQDGSKDHQ GRPLRNFTGI SRVRSITIFP PAINIMPALS RLEVLRVLDL YHCNLGKNSS
LQHRLRDVGH LIHLRYLGLA GTKISELPAE IGNLQFLEVL DLEDNSELRN LSSTICKLRR
LICLHVHRDE VAPGVLQNLT SIEVLRRLVV SLNTVAQELG NLVRLRELLV CFINVGLDLY
EGFVKSVCNL HHIESLRIYS VRASSELMDL LGERWVPPGH LRRFEAHMPS QLSALRGWIM
RDPLHLSNLS DLVLTSVKEV QQEDMEIIGG LLSLRGLQIK STQQTQRLLV IRADVFRCMI
CFDLDCGSGA QIVFEPGALP RTEGLRFSLG VRVTKEDGNH GFDLGLQGNL LSLRTFVWVQ
IYCGGARVGE AKEADAVVRH TLRSHPNHPG IISLMFNMIP NIAEDAHDDD LCEHEEKKEC
DFL
//
