ID Q8MIS3_DIDMR Unreviewed; 504 AA.
AC Q8MIS3;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Venom myotoxin inhibitor DM64 {ECO:0000313|EMBL:AAL82794.1};
OS Didelphis marsupialis (Southern opossum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Didelphimorphia; Didelphidae; Didelphis.
OX NCBI_TaxID=9268 {ECO:0000313|EMBL:AAL82794.1};
RN [1] {ECO:0000313|EMBL:AAL82794.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Liver {ECO:0000313|EMBL:AAL82794.1};
RX PubMed=12473101; DOI=10.1046/j.1432-1033.2002.03308.x;
RA Rocha S.L., Lomonte B., Neves-Ferreira A.G., Trugilho M.R.,
RA Junqueira-de-Azevedo I.d.e. .L., Ho P.L., Domont G.B., Gutierrez J.M.,
RA Perales J.;
RT "Functional analysis of DM64, an antimyotoxic protein with immunoglobulin-
RT like structure from Didelphis marsupialis serum.";
RL Eur. J. Biochem. 269:6052-6062(2002).
RN [2] {ECO:0000313|EMBL:AAL82794.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Liver {ECO:0000313|EMBL:AAL82794.1};
RA Rocha S.L.G., Neves-Ferreira A.G.C., Trugilho M.R.O.,
RA Junqueira-de-Azevedo I.L.M., Ho P.L., Domont G.B., Perales J.;
RL Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AY078384; AAL82794.1; -; mRNA.
DR AlphaFoldDB; Q8MIS3; -.
DR SMR; Q8MIS3; -.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR016332; A1B_glyco/leuk_Ig-like_rcpt.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11738; MHC CLASS I NK CELL RECEPTOR; 1.
DR PANTHER; PTHR11738:SF189; OSTEOCLAST-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13895; Ig_2; 2.
DR PIRSF; PIRSF001979; Alpha_1B_glycoprot_prd; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR001979-1};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..504
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004313913"
FT DOMAIN 31..116
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 210..285
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 314..401
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 409..494
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DISULFID 51..97
FT /evidence="ECO:0000256|PIRSR:PIRSR001979-1"
FT DISULFID 144..186
FT /evidence="ECO:0000256|PIRSR:PIRSR001979-1"
SQ SEQUENCE 504 AA; 55976 MW; 0446529A6CBA63B9 CRC64;
MAAPFILLFF LGLWLDPKAE VDALLAMETT PRLWIETESP STPWTNVTLQ CVATNTEALS
FQLWKDGELL STLPPMGLVG KFSLGPVTDD NRGLYRCRIL MFENTWTSPS EPVEVTGKEP
LPAPLLRADP GPWILHGLET KLHCQGVLLG MIFDLYQEGE QEPVRSSHTP GTEATFIVNN
TGNYSCLYRA PAPASSVNSA PSETIHVVIP DLLPKPDFHI YDNQVIRPGD SVTFGCWGRF
SGLEFKLFKD GQEVFVPKQS SKDPKHIYFE LTALGPEDGG KYSCRYRFRN GPPIWSEDSK
QLELVLTTET LAKPSLSVEP QETVISRGTK VTMRCQGAQP NVKFVLLKKG SPGHTLVLSS
PESHVDFVLP NILSYDTGNF SCLYVQTEAP FAGSQRSEDV EIRVEGLLPK PTLHPVHPVV
APGRDAILHC SGKIPNAHFQ LFKDGEHEEL EVSVLPIDDH AVNFLLKNIN RQQGGKYRCR
YTTREDPILE SEMSDPAELQ VTGQ
//
