ID Q8MVF0_IXOSC Unreviewed; 94 AA.
AC Q8MVF0;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Putative secreted protein {ECO:0000313|EMBL:AAM93612.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945 {ECO:0000313|EMBL:AAM93612.1};
RN [1] {ECO:0000313|EMBL:AAM93612.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Rhode Island {ECO:0000313|EMBL:AAM93612.1};
RC TISSUE=Salivary gland {ECO:0000313|EMBL:AAM93612.1};
RX PubMed=12177149;
RA Valenzuela J.G., Francischetti I.M., Pham V.M., Garfield M.K., Mather T.N.,
RA Ribeiro J.M.;
RT "Exploring the sialome of the tick Ixodes scapularis.";
RL J. Exp. Biol. 205:2843-2864(2002).
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DR EMBL; AF483690; AAM93612.1; -; mRNA.
DR AlphaFoldDB; Q8MVF0; -.
DR VEuPathDB; VectorBase:ISCP_004872; -.
DR VEuPathDB; VectorBase:ISCW007528; -.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0044562; P:envenomation resulting in negative regulation of voltage-gated potassium channel activity in another organism; IEA:UniProt.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 1.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR Pfam; PF00014; Kunitz_BPTI; 1.
DR SMART; SM00131; KU; 1.
DR SUPFAM; SSF57362; BPTI-like; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 1.
PE 2: Evidence at transcript level;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..94
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004311588"
FT DOMAIN 26..77
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
SQ SEQUENCE 94 AA; 9937 MW; 7298B5BF37ED4AAE CRC64;
MKAAIAALCL LAAVVCVIAL LPEGVCRAPH PVSSCASGTP ITTMYYFDNH TDRCQNYLGC
GGGYNDFGSL GCCMDSCPYG RHHPPGKRGK GRKL
//
