ID Q8NBY8_HUMAN Unreviewed; 324 AA.
AC Q8NBY8;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=cDNA FLJ90654 fis, clone PLACE1004520, highly similar to Human pregnancy-specific beta-glycoprotein d mRNA {ECO:0000313|EMBL:BAC11426.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAC11426.1};
RN [1] {ECO:0000313|EMBL:BAC11426.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Placenta {ECO:0000313|EMBL:BAC11426.1};
RX PubMed=16303743; DOI=10.1093/dnares/12.2.117;
RA Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J.,
RA Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S.,
RA Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y.,
RA Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S.,
RA Isogai T.;
RT "Signal sequence and keyword trap in silico for selection of full-length
RT human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA
RT libraries.";
RL DNA Res. 12:117-126(2005).
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. CEA family.
CC {ECO:0000256|ARBA:ARBA00038222}.
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DR EMBL; AK075135; BAC11426.1; -; mRNA.
DR AlphaFoldDB; Q8NBY8; -.
DR PeptideAtlas; Q8NBY8; -.
DR GO; GO:0007565; P:female pregnancy; IEA:UniProtKB-KW.
DR CDD; cd20948; IgC2_CEACAM5-like; 1.
DR CDD; cd05740; IgI_hCEACAM_2_4_6_like; 1.
DR CDD; cd05774; IgV_CEACAM_D1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44427; CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19; 1.
DR PANTHER; PTHR44427:SF16; PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 1; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 2: Evidence at transcript level;
KW Pregnancy {ECO:0000313|EMBL:BAC11426.1}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..324
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004311733"
FT DOMAIN 147..234
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 242..317
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 324 AA; 36622 MW; 4D35AFD0166AA1CB CRC64;
MGTLSAPPCT QRIKWKGLLL TASLLNFWNL PTTAQVTIEA QPPKVSEGKD VLLLVHNLPQ
NLTGYIWYKG QMRDLYHYIT SYVVDGEIII YGPAYSGRET AYSNASLLIQ NVTREDAGSY
TLHIIKGDDG TRGVTGRFTF TLHPKLPKPY ITINNLNPRE NKDVLNFTCE PKSENYTYIW
WLNGQSLPVS PRVKRPIENR ILILPSVTRN ETGPYQCEIR DRYGGVRSDP VTLNVLYGPD
LPRIYPSFTY YRSGEVLYLS CSADSNPPAQ YSWTINEKFQ LPGQKLFIRH ITTKHSGLYV
CSVRNSATGK ESSKSMTVEV SEAL
//
