ID Q8Q048_METMA Unreviewed; 182 AA.
AC Q8Q048;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE RecName: Full=Phosphoesterase {ECO:0000256|RuleBase:RU362039};
DE EC=3.1.4.- {ECO:0000256|RuleBase:RU362039};
GN OrderedLocusNames=MM_0290 {ECO:0000313|EMBL:AAM29986.1};
OS Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS 11833 / OCM 88) (Methanosarcina frisia).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=192952 {ECO:0000313|EMBL:AAM29986.1, ECO:0000313|Proteomes:UP000000595};
RN [1] {ECO:0000313|EMBL:AAM29986.1, ECO:0000313|Proteomes:UP000000595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88
RC {ECO:0000313|Proteomes:UP000000595};
RX PubMed=12125824;
RA Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA Martinez-Arias R., Henne A., Wiezer A., Baumer S., Jacobi C.,
RA Bruggemann H., Lienard T., Christmann A., Bomeke M., Steckel S.,
RA Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.P., Gunsalus R.P.,
RA Fritz H.J., Gottschalk G.;
RT "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT between Bacteria and Archaea.";
RL J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
CC -!- COFACTOR:
CC Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC Evidence={ECO:0000256|RuleBase:RU362039};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. YfcE
CC family. {ECO:0000256|RuleBase:RU362039}.
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DR EMBL; AE008384; AAM29986.1; -; Genomic_DNA.
DR RefSeq; WP_011032244.1; NC_003901.1.
DR AlphaFoldDB; Q8Q048; -.
DR GeneID; 66134979; -.
DR KEGG; mma:MM_0290; -.
DR PATRIC; fig|192952.21.peg.357; -.
DR eggNOG; arCOG01141; Archaea.
DR HOGENOM; CLU_063749_3_2_2; -.
DR Proteomes; UP000000595; Chromosome.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00841; MPP_YfcE; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR024654; Calcineurin-like_PHP_lpxH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041802; MPP_YfcE.
DR InterPro; IPR000979; Phosphodiesterase_MJ0936/Vps29.
DR NCBIfam; TIGR00040; yfcE; 1.
DR PANTHER; PTHR11124:SF12; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 29; 1.
DR PANTHER; PTHR11124; VACUOLAR SORTING PROTEIN VPS29; 1.
DR Pfam; PF12850; Metallophos_2; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 3: Inferred from homology;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW Metal-binding {ECO:0000256|RuleBase:RU362039};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839}.
FT DOMAIN 1..142
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF12850"
SQ SEQUENCE 182 AA; 20134 MW; 67441CC9EEE53D7C CRC64;
MKLIILSDTH LKTGEIPGQL QTLLEDCDLI VHAGDFSTVE AYRAFNASGK LKAVSGNDDS
PELRKLLPER LKFEVEGVRI GVVHEAGLSV MDTTAQGYLA KEMEVDVLIF GHLHRPIIER
KDVMLVCPGS PTKPRMSNPG VVELIIEKGS IEGRIITLEG DSCGYIKFRD ALKRQKEEEG
HK
//
