ID Q8RDV0_FUSNN Unreviewed; 1018 AA.
AC Q8RDV0;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Serine/threonine kinase {ECO:0000313|EMBL:AAL95593.1};
GN OrderedLocusNames=FN1400 {ECO:0000313|EMBL:AAL95593.1};
OS Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 /
OS BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355).
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=190304 {ECO:0000313|EMBL:AAL95593.1, ECO:0000313|Proteomes:UP000002521};
RN [1] {ECO:0000313|EMBL:AAL95593.1, ECO:0000313|Proteomes:UP000002521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 /
RC KCTC 2640 / LMG 13131 / VPI 4355 {ECO:0000313|Proteomes:UP000002521};
RX PubMed=11889109; DOI=10.1128/JB.184.7.2005-2018.2002;
RA Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A.,
RA Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O.,
RA Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N., D'Souza M.,
RA Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N., Overbeek R.;
RT "Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum
RT strain ATCC 25586.";
RL J. Bacteriol. 184:2005-2018(2002).
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DR EMBL; AE009951; AAL95593.1; -; Genomic_DNA.
DR RefSeq; NP_604294.1; NC_003454.1.
DR RefSeq; WP_011017124.1; NZ_CP028101.1.
DR AlphaFoldDB; Q8RDV0; -.
DR STRING; 190304.FN1400; -.
DR PaxDb; 190304-FN1400; -.
DR EnsemblBacteria; AAL95593; AAL95593; FN1400.
DR GeneID; 79784371; -.
DR KEGG; fnu:FN1400; -.
DR PATRIC; fig|190304.8.peg.1961; -.
DR eggNOG; COG3629; Bacteria.
DR eggNOG; COG3899; Bacteria.
DR HOGENOM; CLU_004435_1_2_0; -.
DR InParanoid; Q8RDV0; -.
DR BioCyc; FNUC190304:G1FZS-1971-MONOMER; -.
DR Proteomes; UP000002521; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004016; F:adenylate cyclase activity; IBA:GO_Central.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF03704; BTAD; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AAL95593.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002521};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transferase {ECO:0000313|EMBL:AAL95593.1}.
FT DOMAIN 97..229
FT /note="Bacterial transcriptional activator"
FT /evidence="ECO:0000259|SMART:SM01043"
FT REPEAT 835..868
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 1018 AA; 120077 MW; AF24044EF6B0ED5E CRC64;
MTKIICKLFG SPKIYEDKKE IFLPSGKLTA FFYYLLLKKV VSRDEVAGMF WASSNEQNAK
ISLRNALHKI RKSFKEDIIL SPNKSILTLN KDLDIDIDAE KFQKDPLNNF SLYNGDFLKG
FYVKEAIDFD YWVLEINTFY KELFIKTAEK KIEEDFLQSR FENLETSITS LLTADNFNDK
AYLYLMKFYK QKGRYDKIIN EYKNIQKLME EELGIDPPDE IKNIYKEALK CIEKNKEINI
KKNTMDIYCR DFELDSIQLN LDNFQKKFSN KSILITGESG IGKTILKKEI LNRNSGKFKI
FETACFSMEK DFSYLPWTNI IRDMENELLK FNLKRPHLWD NILKNLFFDG ANNIQPSIEI
LENKENFNID LIYNSIYSAL DILSKEKKII IVFEDIQWAD QLSIKLLINL ILHIHSNVLF
ILTKTNSIDT VTDRLFLTLK DLNKILLIDL KPFSKRDIAL IIKKNFSQKN ISNEEIDEIF
EKSKGNPFFL KEYIELFKKN KKNNEITSKL HNVLQEKFLN LTENEMNILK IISVFYGDVN
LDTLLKLINL KAFEALKFLN LLIEKNIIEE KKKDSKVIIT FTYSAYKDYI FNEMNDSSKQ
IINMEIAKTL EEELSNLNNI ATYNKLKYHY QKANVNIKTL KYDVYILNYY LNFNHEIFPN
LDDYDLSKQV KLFIGNDKAN KWMNEIKKEL MLVKKSKMNS LDIQEIKKIE LIFMYCKGRY
LIREGSYTDG INLMNRVISI AKDLKEEKIQ ISAHKQMAIY AIQINNYQIM LKHIIEGIKI
ARKEKTVDVG IFYRLYGVYY LIRDEFKTAE SLFKKSIELF LEFERIGDKN SISIAANYNY
IGEIRNSEGN FEEAMELFNK AIKLCENYEA SCLSTFYINA GKTSYLIGNF QDMKKFFLLA
EKIIKNFDSY WKNSVLNAFL ALDAFLENDN LKVIHYLKCA ISEGKIINNP RDIGMVYFVE
AIIIYSIEIK NIKKYEDIKK ILEENSNFYY YKAIKYLDST RDKSEIEYLK NFLNINKI
//
