ID Q8RG73_FUSNN Unreviewed; 574 AA.
AC Q8RG73;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=Phosphoadenosine phosphosulfate reductase {ECO:0000313|EMBL:AAL94640.1};
DE EC=1.8.4.8 {ECO:0000313|EMBL:AAL94640.1};
GN OrderedLocusNames=FN0444 {ECO:0000313|EMBL:AAL94640.1};
OS Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 /
OS BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355).
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=190304 {ECO:0000313|EMBL:AAL94640.1, ECO:0000313|Proteomes:UP000002521};
RN [1] {ECO:0000313|EMBL:AAL94640.1, ECO:0000313|Proteomes:UP000002521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 /
RC KCTC 2640 / LMG 13131 / VPI 4355 {ECO:0000313|Proteomes:UP000002521};
RX PubMed=11889109; DOI=10.1128/JB.184.7.2005-2018.2002;
RA Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A.,
RA Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O.,
RA Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N., D'Souza M.,
RA Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N., Overbeek R.;
RT "Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum
RT strain ATCC 25586.";
RL J. Bacteriol. 184:2005-2018(2002).
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DR EMBL; AE009951; AAL94640.1; -; Genomic_DNA.
DR RefSeq; NP_603341.1; NC_003454.1.
DR RefSeq; WP_011016392.1; NZ_CP028101.1.
DR AlphaFoldDB; Q8RG73; -.
DR STRING; 190304.FN0444; -.
DR PaxDb; 190304-FN0444; -.
DR EnsemblBacteria; AAL94640; AAL94640; FN0444.
DR GeneID; 79783453; -.
DR KEGG; fnu:FN0444; -.
DR PATRIC; fig|190304.8.peg.1014; -.
DR eggNOG; COG0175; Bacteria.
DR eggNOG; COG2221; Bacteria.
DR eggNOG; COG5270; Bacteria.
DR HOGENOM; CLU_478906_0_0_0; -.
DR InParanoid; Q8RG73; -.
DR BioCyc; FNUC190304:G1FZS-1037-MONOMER; -.
DR Proteomes; UP000002521; Chromosome.
DR GO; GO:0004604; F:phosphoadenylyl-sulfate reductase (thioredoxin) activity; IEA:UniProtKB-EC.
DR CDD; cd01713; PAPS_reductase; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR002500; PAPS_reduct.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR43196; SULFATE ADENYLYLTRANSFERASE SUBUNIT 2; 1.
DR PANTHER; PTHR43196:SF1; SULFATE ADENYLYLTRANSFERASE SUBUNIT 2; 1.
DR Pfam; PF01507; PAPS_reduct; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:AAL94640.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002521}.
FT DOMAIN 507..537
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 574 AA; 66665 MW; 16CB867B8F4C6885 CRC64;
MWCKTCNIET NEKVCPICKS NTVEDLPVEV YWCKKCKIPI IKQINQVDKE ICPICNGKAE
YLSKDIRPVF PEERLLLELL LEKEANSLIN CSIWASDNKY FIDGKKKIIQ NKLFNELEPK
IFKKKLDEYG KYNSYEKFNE QIIEFVKANK FRYLYLVDEA NEFIKKTAKK YEEEKIVISF
SGGKDSTVVA DLVINALGNP SLVHIFGDTT LEFQTTMEYA ERYRASHRQA IFQIAKNNEQ
NFMSVCNDIG PPARMMRWCC SMFKTGPITR VLNNLYREER ILTFYGIRKS ESLSRSKYNR
VEGNSESVKI QKQTVASPIF FWSDIDIWLY ILTRKIDFNE AYRRGYDRVG CWCCPNNNIR
AQFMSTIYMP EKSKEWRNFL IEFAKRIGKA DAENYVDTGM WKARQGGNGL ASASDIKIKF
TNCTTEEHAK IYKTKEIINE EFINLFIPFG KIAPELGQKL LQEVIILDYK TNIPIISIQP
FGKDTEGYSV KIKTINVSDH ENLQKMIAYQ VKKFNACRKC LKCESICKVG AISITGNNYY
INASKCVHCK MCVNPKYLSG GCMMDKYLRT KEKK
//
