ID Q8RNB6_BARHN Unreviewed; 219 AA.
AC Q8RNB6;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN Name=pcm {ECO:0000313|EMBL:AAL89760.1};
OS Bartonella henselae (Rochalimaea henselae).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Bartonellaceae; Bartonella.
OX NCBI_TaxID=38323 {ECO:0000313|EMBL:AAL89760.1};
RN [1] {ECO:0000313|EMBL:AAL89760.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Houston-1 {ECO:0000313|EMBL:AAL89760.1};
RX PubMed=12941162; DOI=10.1089/104454903322216699;
RA Padmalayam I., Fiskus W., Massung R.F., Baumstark B.R.;
RT "Molecular cloning and analysis of a region of the Bartonella bacilliformis
RT genome encoding NlpD, L-isoaspartyl methyltransferase and YajC homologs.";
RL DNA Cell Biol. 22:347-353(2003).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF484425; AAL89760.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8RNB6; -.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:AAL89760.1};
KW Transferase {ECO:0000313|EMBL:AAL89760.1}.
SQ SEQUENCE 219 AA; 25147 MW; 67839DF83466ADD5 CRC64;
MEQKDILQFR EKLASLVLKM RSKGIDDVNF FAAFEKIPRQ YFVSSPWLNS AYDNKVIPIE
CGEYIERLEE QLLILFALSL RKKHRVLEIG TGSGFCSALI AYLSDRVVTV DRYKTLVDLA
RQKFQTLGIE NIVVHQIDGS RGVTGFGLFD RILIWPSRSD EPKEFLELLT ENGILIQAIG
PDEGVQTITR YTKIASRFEC LEMFQVRYQP FIEGIAETL
//
