ID   Q8RTP6_STRLI            Unreviewed;       219 AA.
AC   Q8RTP6;
DT   01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2002, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Putative 1-deoxy-D-xylulose 5-phosphate synthase {ECO:0000313|EMBL:AAL77237.1};
DE   Flags: Fragment;
GN   Name=dxsA {ECO:0000313|EMBL:AAL77237.1};
OS   Streptomyces lividans.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1916 {ECO:0000313|EMBL:AAL77237.1};
RN   [1] {ECO:0000313|EMBL:AAL77237.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Li S.-M., Wemakor E., Heide L.;
RT   "PCR Amplification of 1-Deoxy-D-Xylulose 5-Phosphate Synthase (dxs) Genes
RT   from Different Streptomyces species: Evidence for the Existence of Two dxs
RT   Gene Families.";
RL   Mol. Biol. Today 2:61-66(2001).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
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DR   EMBL; AF283715; AAL77237.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8RTP6; -.
DR   GO; GO:0008661; F:1-deoxy-D-xylulose-5-phosphate synthase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR   GO; GO:0016114; P:terpenoid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.970; -; 2.
DR   InterPro; IPR005477; Dxylulose-5-P_synthase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   PANTHER; PTHR43322; 1-D-DEOXYXYLULOSE 5-PHOSPHATE SYNTHASE-RELATED; 1.
DR   PANTHER; PTHR43322:SF5; 1-DEOXY-D-XYLULOSE-5-PHOSPHATE SYNTHASE, CHLOROPLASTIC; 1.
DR   Pfam; PF13292; DXP_synthase_N; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE   4: Predicted;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842}.
FT   DOMAIN          166..219
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02779"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAL77237.1"
FT   NON_TER         219
FT                   /evidence="ECO:0000313|EMBL:AAL77237.1"
SQ   SEQUENCE   219 AA;  23904 MW;  850CA07B803E50BD CRC64;
     GMAWEALNNI AAAKDRPLVI VVNDNERSYA PTIGGLANHL ATLRTTDGYE RFLARTKEVL
     ERTPVVGRPL YDTLHGAKKG LKDFIAPQGM FEDLGLKYVG PIDGHDLEAL ESALTRAKRF
     GGPVIVHCLT EKGRGYQPAL QDEADRFHAV GKIHPDTGLP ISTSGADWTS VFGDEMLKLG
     KEREDVVAIT AAMLQPVGLD KFAKAFPDRV YDVAIAEQH
//