ID Q8RW72_9MYRT Unreviewed; 501 AA.
AC Q8RW72;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|ARBA:ARBA00011952, ECO:0000256|RuleBase:RU000612};
DE EC=5.3.1.9 {ECO:0000256|ARBA:ARBA00011952, ECO:0000256|RuleBase:RU000612};
DE Flags: Fragment;
GN Name=pgiC1 {ECO:0000313|EMBL:CAC86121.1};
OS Clarkia modesta.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Onagraceae; Onagroideae; Onagreae; Clarkia.
OX NCBI_TaxID=165267 {ECO:0000313|EMBL:CAC86121.1};
RN [1] {ECO:0000313|EMBL:CAC86121.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LDG-8612-2b {ECO:0000313|EMBL:CAC86121.1};
RX PubMed=12038528;
RA Ford V.S., Gottlieb L.D.;
RT "Single mutations silence PGiC2 genes in two very recent allotetraploid
RT species of Clarkia.";
RL Evolution 56:699-707(2002).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate;
CC Xref=Rhea:RHEA:11816, ChEBI:CHEBI:57634, ChEBI:CHEBI:58225;
CC EC=5.3.1.9; Evidence={ECO:0000256|ARBA:ARBA00029321,
CC ECO:0000256|RuleBase:RU000612};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 2/4.
CC {ECO:0000256|ARBA:ARBA00004926, ECO:0000256|RuleBase:RU000612}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the GPI family. {ECO:0000256|ARBA:ARBA00006604,
CC ECO:0000256|RuleBase:RU000612}.
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DR EMBL; AJ312367; CAC86121.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8RW72; -.
DR UniPathway; UPA00109; UER00181.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR CDD; cd05015; SIS_PGI_1; 1.
DR CDD; cd05016; SIS_PGI_2; 1.
DR HAMAP; MF_00473; G6P_isomerase; 1.
DR InterPro; IPR001672; G6P_Isomerase.
DR InterPro; IPR018189; Phosphoglucose_isomerase_CS.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR035476; SIS_PGI_1.
DR InterPro; IPR035482; SIS_PGI_2.
DR PANTHER; PTHR11469; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR11469:SF1; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF00342; PGI; 1.
DR PRINTS; PR00662; G6PISOMERASE.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS00765; P_GLUCOSE_ISOMERASE_1; 1.
DR PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 1.
PE 3: Inferred from homology;
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432,
KW ECO:0000256|RuleBase:RU000612};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152, ECO:0000256|RuleBase:RU000612};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU000612}.
FT NON_TER 501
FT /evidence="ECO:0000313|EMBL:CAC86121.1"
SQ SEQUENCE 501 AA; 55304 MW; 0BCD727224E7F664 CRC64;
MASPALISET EAWKDLKAHL EDIKMTHLRE LMGDTERCQS MMVEFDNIFL DYSRQQASPD
TISKLYKLAD AAHLKQKIDR MYNGDHINTT ENRSVLHVAL RAPRNSAICS DGKNVVPDVW
NVLDKIKDFS DRVRNGSWIG ATGKKLKDVI AVGIGGSFLG PLFVHTALQT DPESSKNARG
RELRFLANVD PIDVARNISG LNPETTLVVV VSKTFTTAET MLNARTLREW ISSALGPSAV
AKHMVAVSTN LPLVEKFGID PNNAFAFWDW VGGRYSVCSA VGVLPLSLQY GFAVVEKFLQ
GAHSIDQHFS SAPFEKNVPV LLGLLSVWNV SFLGYPARAI LPYSQALEKL APHIQQVSME
SNGKGVSIDG LPLPFESGEI DFGEPGTNGQ HSFYQLIHQG RVIPCDFIGV VKSQQPVYLK
GEVVNNHDEL MSNFFAQPDA LAYGKTPEQL KKENVSEHLI PHKTFTGNRP SISILLPTLD
AYRIGQLLAI YEHRVAVQGF V
//
