ID Q8SDG3_9CAUD Unreviewed; 600 AA.
AC Q8SDG3;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 01-MAY-2013, entry version 59.
DE RecName: Full=Lysozyme;
DE EC=3.2.1.17;
GN Name=5;
OS Enterobacteria phage RB49.
OC Viruses; dsDNA viruses, no RNA stage; Caudovirales; Myoviridae;
OC Tevenvirinae; T4likevirus.
OX NCBI_TaxID=50948;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=9096222; DOI=10.1006/jmbi.1996.0867;
RA Monod C., Repoila F., Kutateladze M., Tetart F., Krisch H.M.;
RT "The genome of the pseudo T-even bacteriophages, a diverse group that
RT resembles T4.";
RL J. Mol. Biol. 267:237-249(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=10217762;
RA Kanamaru S., Gassner N.C., Ye N., Takeda S., Arisaka F.;
RT "The C-terminal fragment of the precursor tail lysozyme of
RT bacteriophage T4 stays as a structural component of the baseplate
RT after cleavage.";
RL J. Bacteriol. 181:2739-2744(1999).
RN [3]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11092834; DOI=10.1146/annurev.genet.34.1.439;
RA Ang D., Keppel F., Klein G., Richardson A., Georgopoulos C.;
RT "Genetic analysis of bacteriophage-encoded cochaperonins.";
RL Annu. Rev. Genet. 34:439-456(2000).
RN [4]
RP NUCLEOTIDE SEQUENCE.
RA Ang D., Richardson A., Mayer M.P., Keppel F., Krisch H.,
RA Georgopoulos C.;
RL Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE.
RA Zhao L., Tetart F., Krisch H.M., Arisaka F.;
RL Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE.
RA Thiemer C.A., Desplats C., Dez C., Tetart F., Eleaume H., Krisch H.M.;
RL Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11976309; DOI=10.1128/JB.184.10.2789-2804.2002;
RA Desplats C., Dez C., Tetart F., Eleaume H., Krisch H.M.;
RT "Snapshot of the genome of the pseudo-T-even bacteriophage RB49.";
RL J. Bacteriol. 184:2789-2804(2002).
RN [8]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11823865; DOI=10.1038/415553a;
RA Kanamaru S., Leiman P.G., Kostyuchenko V.A., Chipman P.R.,
RA Mesyanzhinov V.V., Arisaka F., Rossmann M.G.;
RT "Structure of the cell-puncturing device of bacteriophage T4.";
RL Nature 415:553-557(2002).
RN [9]
RP NUCLEOTIDE SEQUENCE.
RA Namiki H., Zhao L., Arisaka F.;
RT "gp5, the tail lysozyme in RB49.";
RL Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
RN [10]
RP NUCLEOTIDE SEQUENCE.
RA Letarov A.V., Krisch h.M., Tetart P.;
RL Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
RN [11]
RP NUCLEOTIDE SEQUENCE.
RA Bertrand C., Petrov V., Nolan J., Letarov A., Desplats C., Chin D.,
RA Karam J.D., Krisch H.M.;
RL Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY: Hydrolysis of (1->4)-beta-linkages between N-
CC acetylmuramic acid and N-acetyl-D-glucosamine residues in a
CC peptidoglycan and between N-acetyl-D-glucosamine residues in
CC chitodextrins.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 24 family.
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DR EMBL; AY343333; AAL12619.2; -; Genomic_DNA.
DR EMBL; AB084150; BAB90980.1; -; Genomic_DNA.
DR RefSeq; NP_891705.1; NC_005066.1.
DR HSSP; P00720; 103L.
DR ProteinModelPortal; Q8SDG3; -.
DR CAZy; GH24; Glycoside Hydrolase Family 24.
DR GeneID; 1725506; -.
DR ProtClustDB; PHA2596; -.
DR GO; GO:0003796; F:lysozyme activity; IEA:EC.
DR GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
DR GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR Gene3D; 1.10.530.40; -; 1.
DR InterPro; IPR002196; Glyco_hydro_24.
DR InterPro; IPR010609; Gp5_C.
DR InterPro; IPR009590; Gp5_OB_N_virus.
DR InterPro; IPR023346; Lysozyme-like_dom.
DR InterPro; IPR023347; Lysozyme_dom.
DR InterPro; IPR001165; Phage_T4_Gp5_lysozyme.
DR Pfam; PF06715; Gp5_C; 1.
DR Pfam; PF06714; Gp5_OB; 1.
DR Pfam; PF00959; Phage_lysozyme; 1.
DR PRINTS; PR00684; T4LYSOZYME.
DR SUPFAM; SSF53955; SSF53955; 1.
PE 3: Inferred from homology;
KW Antimicrobial; Bacteriolytic enzyme; Glycosidase; Hydrolase.
SQ SEQUENCE 600 AA; 66378 MW; 8CEB78B76D1AAACE CRC64;
MLMFNNSVKW FTGIVENRED PLMLGRVQVR IHGIHPSLSA HGDIQGLPTE DLLWITPVQD
ITSAAISGIG QSPTGIVEGS MVFGLALDER YLNCVILGTI AGQYTEKPLT TEGFCDPSGA
YPRYIGNDVN ILARGGINPE TGQTTKPDSV YIRDENTGVA VNPDDEPLDQ IPVDDNPDFT
IEKMLRGDEG YREKWYLDSE GYPTIGIGHL IIYKKTSDLG IINNELSKLV GREVTNGRLT
AEEVSKVFAD DIEKTRRDMR KHPRIAPVYN KCNASRRMAL ENMAFQMGVG GLGKFKNSLA
AMLAEEWKQA YDGLRQSVWA NQTPGRSSRV SKIILTGNLE SYGVIAPKKE ESISDDPRAR
LRNARIAAYK TQRAEEEDPE APFTPQDTRI MFKEPKSSYS ARYPYNHVYE SESGHIIEID
DTPSHERYHR KHPSGTFEET RPDGTRVEKI EGDDYLIVKQ GRKVNVKGNL QVVVEGDAQV
YYMGNVMQTV DGNVTEFIRG NVNQTVEGTA NMHVVGDVTA QLDANLTANV KGNAELMIEG
NTTETIKGNY DLTVEGNFNM TVNGTKSDQV NGDWSRNCGA SVKDIASGTV KIDGSRIDLG
//
