ID   Q8SQW7_ENCCU            Unreviewed;       664 AA.
AC   Q8SQW7;
DT   01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2002, sequence version 1.
DT   27-MAR-2024, entry version 123.
DE   SubName: Full=Possible PRE-mRNA SPLICING FACTOR (ATP-DEPENDENT RNA HELICASE) {ECO:0000313|EMBL:CAD25996.1};
GN   OrderedLocusNames=ECU11_0860 {ECO:0000313|EMBL:CAD25996.1};
OS   Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=284813 {ECO:0000313|EMBL:CAD25996.1, ECO:0000313|Proteomes:UP000000819};
RN   [1] {ECO:0000313|EMBL:CAD25996.1, ECO:0000313|Proteomes:UP000000819}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GB-M1 {ECO:0000313|EMBL:CAD25996.1,
RC   ECO:0000313|Proteomes:UP000000819};
RX   PubMed=11719806; DOI=10.1038/35106579;
RA   Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA   Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA   Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA   Vivares C.P.;
RT   "Genome sequence and gene compaction of the eukaryote parasite
RT   Encephalitozoon cuniculi.";
RL   Nature 414:450-453(2001).
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DR   EMBL; AL590450; CAD25996.1; -; Genomic_DNA.
DR   RefSeq; NP_586392.1; NM_001042225.1.
DR   AlphaFoldDB; Q8SQW7; -.
DR   STRING; 284813.Q8SQW7; -.
DR   GeneID; 860045; -.
DR   KEGG; ecu:ECU11_0860; -.
DR   VEuPathDB; MicrosporidiaDB:ECU11_0860; -.
DR   HOGENOM; CLU_001832_5_11_1; -.
DR   InParanoid; Q8SQW7; -.
DR   OMA; EANECGC; -.
DR   OrthoDB; 3682876at2759; -.
DR   Proteomes; UP000000819; Chromosome XI.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd17917; DEXHc_RHA-like; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:CAD25996.1};
KW   Hydrolase {ECO:0000313|EMBL:CAD25996.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000819}.
FT   DOMAIN          67..226
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          244..415
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   664 AA;  74709 MW;  65FB71D9D37DA447 CRC64;
     MKKMAAAESM EAEICINREI PPGLFPAVKG TDDLMAEGDI MSLLESIKKT EGGSGEVSVE
     DKMDEIFAKL EKSQVLLIQG DTGCGKTTKI PKYLLRKYGK IVCSQPRRIA AVSIAKKVAV
     DMKGKIGEDV GYSIRFDDMS SGRTRLKYVT DGVLLREIKN DKHLKKYDVV IIDEAHERSV
     NIDILLGYLK SILSERKDLR VVIMSATLNS EKFASFFRCQ TVEIRHRMFP LEIFFLKKSD
     VADYVDEAMK TVVQIHRGEE SGDILVFLTG RDEINSGREI LMEVLGNDAE VCCIYSTLSP
     EEQEAVFRKT KKRKIVLATN IAETSITIEG VRYVVDSGRA KQMRYSASFG MDILEVVWIS
     KAQAKQRAGR AGRTQAGKVF RMYSKEEYQK MDDNTTPEIF CCNLGKIVLE LKSIGVDDIV
     NFNLIDKPDA SNVKKALEML YYLRAIGGDG KITSIGVKAS TIPLDPELAV SLIVSSELGC
     LEDVSIIAAM LSVGNVWLDV PRYSQSYKAF LGARAAHFDK RGDHFLLLKI YRRWEKTGFK
     ISHLKRWFLN VKTMLQTVKI KKQLCSMFRS PCKSDESGIL PSLCAGYFMN VAKLVGESYV
     SIFNDTPCFI HYTSCMSRQN AKYILYHTLC RTGKEYARYC VGVTLEDLLK GANHMFAKVR
     KTEK
//