ID Q8SSA1_ENCCU Unreviewed; 270 AA.
AC Q8SSA1;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 2.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=NUCLEOLAR PROTEIN OF THE GAR FAMILY {ECO:0000313|EMBL:CAD26218.2};
GN OrderedLocusNames=ECU03_0730 {ECO:0000313|EMBL:CAD26218.2};
OS Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC Encephalitozoon.
OX NCBI_TaxID=284813 {ECO:0000313|EMBL:CAD26218.2, ECO:0000313|Proteomes:UP000000819};
RN [1] {ECO:0000313|EMBL:CAD26218.2, ECO:0000313|Proteomes:UP000000819}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GB-M1 {ECO:0000313|EMBL:CAD26218.2,
RC ECO:0000313|Proteomes:UP000000819};
RX PubMed=11719806; DOI=10.1038/35106579;
RA Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA Vivares C.P.;
RT "Genome sequence and gene compaction of the eukaryote parasite
RT Encephalitozoon cuniculi.";
RL Nature 414:450-453(2001).
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DR EMBL; AL590443; CAD26218.2; -; Genomic_DNA.
DR RefSeq; NP_597583.1; NM_001040947.1.
DR AlphaFoldDB; Q8SSA1; -.
DR GeneID; 858745; -.
DR KEGG; ecu:ECU03_0730; -.
DR VEuPathDB; MicrosporidiaDB:ECU03_0730; -.
DR HOGENOM; CLU_1019525_0_0_1; -.
DR InParanoid; Q8SSA1; -.
DR OrthoDB; 249213at2759; -.
DR Proteomes; UP000000819; Chromosome III.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00590; RRM_SF; 2.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR48027; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED; 1.
DR PANTHER; PTHR48027:SF30; RRM DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000819};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 64..141
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 148..217
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 222..238
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 270 AA; 30801 MW; B25BF7EA0BA352D3 CRC64;
MKKTMEKVSK SNSVSETESD SEAPTGSSSS GMEETSNLEG SSTEIEEETS SGSGEESRRE
NPSLTVFIKG ISYDLTEYDL KSEMEKIGKV ARVGIPMTND HKRNKGFGYV EFCKEEDVKK
ALKLDGTVFL GREVVVNMAH PRANKERHTI YVSNIPYECD KRDLKKYFEG MGEVVGMSLP
YDRDNNRLKG YGFVDFGNKE DYERVLKKKL VFEDSTMYHR PAYKNNREDR RDSNGRGFKR
SDSNWSGKRY GAEGQNRNNK KVKFNSDSEE
//
