ID Q8T4C8_DROME Unreviewed; 550 AA.
AC Q8T4C8;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 2.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=AT03646p {ECO:0000313|EMBL:AAL89989.2};
DE Flags: Fragment;
GN Name=CycT-RB {ECO:0000313|EMBL:AAL89989.2};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AAL89989.2};
RN [1] {ECO:0000313|EMBL:AAL89989.2}
RP NUCLEOTIDE SEQUENCE.
RA Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M.,
RA Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R.,
RA Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A.,
RA Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S.,
RA Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S.;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAL89989.2}
RP NUCLEOTIDE SEQUENCE.
RA Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S.;
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cyclin family.
CC {ECO:0000256|RuleBase:RU000383}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY089251; AAL89989.2; -; mRNA.
DR AlphaFoldDB; Q8T4C8; -.
DR PeptideAtlas; Q8T4C8; -.
DR VEuPathDB; VectorBase:FBgn0025455; -.
DR HOGENOM; CLU_283750_0_0_1; -.
DR ExpressionAtlas; Q8T4C8; baseline and differential.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd20538; CYCLIN_CCNT_rpt1; 1.
DR CDD; cd20539; CYCLIN_CCNT_rpt2; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR043198; Cyclin/Ssn8.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10026; CYCLIN; 1.
DR PANTHER; PTHR10026:SF155; CYCLIN-T; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR Pfam; PF21797; CycT2-like_C; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 2: Evidence at transcript level;
KW Cyclin {ECO:0000256|RuleBase:RU000383}.
FT DOMAIN 76..169
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 182..266
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 319..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..351
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..455
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..526
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 550
FT /evidence="ECO:0000313|EMBL:AAL89989.2"
SQ SEQUENCE 550 AA; 60436 MW; EBD8BAB52D383F77 CRC64;
MSLLATPMPQ AATASSSSSA SAAASASGIP ITANNNLPFE KDKIWYFSND QLANSPSRRC
GIKGDDELQY RQMTAYLIQE MGQRLQVSQL CINTAIVYMH RFYAFHSFTH FHRNSMASAS
LFLAAKVEEQ PRKLEHVIRA ANKCLPPTTE QNYAELAQEL VFNENVLLQT LGFDVAIDHP
HTHVVRTCQL VKACKDLAQT SYFLASNSLH LTSMCLQYRP TVVACFCIYL ACKWSRWEIP
QSTEGKHWFY YVDKTVSLDL LKQLTDEFIA IYEKSPARLK SKLNSIKAIA QGASNRTANS
KDKPKEDWKI TEMMKGYHSN ITTPPELLNG NDSRDRDRDR ERERERERDP SSLLPPPAMV
PQQRRQDGGH QRSSSVSGVP GSSSSSSSSS HKMPNYPGGM PPEAHPDHKS KQPGYNNRMP
SSHQRSSSSG LGSSGSGSQR SSSSSSSSSQ QPGRPSMPVD YHKSSRGMPP VGVGMPPHGS
HKMTSGSKPQ QPQQQPVPHP SASNSSASGM SSKDKSQSNK MYPNAPPPYS NSAPQNPLMS
RGGYPGASNG
//
