ID Q8T7S9_PLAFA Unreviewed; 272 AA.
AC Q8T7S9;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 22-FEB-2023, entry version 48.
DE SubName: Full=Merozoite surface protein 4 {ECO:0000313|EMBL:AAL93105.1};
DE Flags: Fragment;
OS Plasmodium falciparum (malaria parasite P. falciparum).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5833 {ECO:0000313|EMBL:AAL93105.1};
RN [1] {ECO:0000313|EMBL:AAL93105.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=902/0 {ECO:0000313|EMBL:AAL93105.1};
RX PubMed=11897136; DOI=10.1016/S0166-6851(01)00457-1;
RA Wang L., Marshall V.M., Coppel R.L.;
RT "Limited polymorphism of the vaccine candidate merozoite surface protein 4
RT of Plasmodium falciparum.";
RL Mol. Biochem. Parasitol. 120:301-303(2002).
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DR EMBL; AF295324; AAL93105.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8T7S9; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR024731; EGF_dom.
DR Pfam; PF12947; EGF_3; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR PROSITE; PS01186; EGF_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Merozoite {ECO:0000313|EMBL:AAL93105.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 230..243
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS01186"
FT REGION 50..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..150
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..200
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 272
FT /evidence="ECO:0000313|EMBL:AAL93105.1"
SQ SEQUENCE 272 AA; 30591 MW; E2F37DB857AB272F CRC64;
MWIVKFLIVV HFFIICTINF DKLYISYSYN IVPENGRMLN MRILGEEKPN VDGVSTSNTP
GGNESSSASP NLSDAAEKKD EKEASEQGEE SHKKENSQES ANGKDDVKEE KKTNEKKDDG
KTDKVQEKVL EKSPKESQMV DDKKKTEAIP KKVVQPSSSN SGGHVGEEED HNEGEGEHEE
EEEHEEDDDV EDDDTYNKDD LEDEDLCKHN NGDCGDDKLC EYVGNRRVKC KCKEGYKLEG
IECVELLSLA SSSLNLIFNS FITIFVVILL IN
//
