ID Q8T8X4_DROME Unreviewed; 483 AA.
AC Q8T8X4;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 119.
DE SubName: Full=AT19278p {ECO:0000313|EMBL:AAL68100.1};
GN Name=l(2)k05911 {ECO:0000313|FlyBase:FBgn0284244};
GN Synonyms=CG16821 {ECO:0000313|EMBL:AAL68100.1};
GN ORFNames=CG31728 {ECO:0000313|FlyBase:FBgn0284244};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AAL68100.1};
RN [1] {ECO:0000313|EMBL:AAL68100.1}
RP NUCLEOTIDE SEQUENCE.
RA Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M.,
RA Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R.,
RA Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A.,
RA Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S.,
RA Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S.;
RL Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AY075233; AAL68100.1; -; mRNA.
DR AlphaFoldDB; Q8T8X4; -.
DR MEROPS; S01.B44; -.
DR UCSC; CG31728-RB; d. melanogaster.
DR AGR; FB:FBgn0284244; -.
DR FlyBase; FBgn0284244; l(2)k05911.
DR VEuPathDB; VectorBase:FBgn0284244; -.
DR HOGENOM; CLU_027986_0_0_1; -.
DR ChiTaRS; CG31851; fly.
DR ExpressionAtlas; Q8T8X4; baseline and differential.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004252; F:serine-type endopeptidase activity; ISM:FlyBase.
DR GO; GO:0006508; P:proteolysis; ISM:FlyBase.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24252; ACROSIN-RELATED; 1.
DR PANTHER; PTHR24252:SF7; HYALIN; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|RuleBase:RU363034};
KW Protease {ECO:0000256|RuleBase:RU363034};
KW Serine protease {ECO:0000256|RuleBase:RU363034}.
FT DOMAIN 244..483
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT REGION 146..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..168
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 483 AA; 52069 MW; E2674FECC9956069 CRC64;
MCNFFDMLGR VNNGICCTDI DANGFGVFPL PGTTTTTTTT TEMPSVVADE EDREHVIPEG
EVEGVYPPDV PRPEEPIDNA NSVEDTPDFQ DINTIEGNAP GADQKPEAEP AMEPVEQPIS
TQPASTIHPY QWPFGSFAGG QWPPALPTHP PTTGGWPPPL PTHPPNHHYP THPTTGGVPS
TKRTTPRPTN PARPTTTRRP TYPSYPSPVT TTTTTRRPVS GTSSEGLPLQ CGNKNPVTPD
QERIVGGINA SPHEFPWIAV LFKSGKQFCG GSLITNSHIL TAAHCVARMT SWDVAALTAH
LGDYNIGTDF EVQHVSRRIK RLVRHKGFEF STLHNDVAIL TLSEPVPFTR EIQPICLPTS
PSQQSRSYSG QVATVAGWGS LRENGPQPSI LQKVDIPIWT NAECARKYGR AAPGGIIESM
ICAGQAAKDS CSGDSGGPMV INDGGRYTQV GIVSWGIGCG KGQYPGVYTR VTSLLPWIYK
NIK
//
