ID Q8TIF0_METAC Unreviewed; 233 AA.
AC Q8TIF0;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE RecName: Full=Calcineurin-like phosphoesterase domain-containing protein {ECO:0000259|Pfam:PF12850};
GN OrderedLocusNames=MA_4202 {ECO:0000313|EMBL:AAM07548.1};
OS Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS C2A).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=188937 {ECO:0000313|EMBL:AAM07548.1, ECO:0000313|Proteomes:UP000002487};
RN [1] {ECO:0000313|EMBL:AAM07548.1, ECO:0000313|Proteomes:UP000002487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A
RC {ECO:0000313|Proteomes:UP000002487};
RX PubMed=11932238; DOI=10.1101/gr.223902;
RA Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA Cann I., Graham D.E., Grahame D.A., Guss A., Hedderich R., Ingram-Smith C.,
RA Kuettner C.H., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B.,
RA Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H.,
RA de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L.,
RA Paulsen I., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H.,
RA Lander E., Metcalf W.W., Birren B.;
RT "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT physiological diversity.";
RL Genome Res. 12:532-542(2002).
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DR EMBL; AE010299; AAM07548.1; -; Genomic_DNA.
DR RefSeq; WP_011024087.1; NC_003552.1.
DR AlphaFoldDB; Q8TIF0; -.
DR STRING; 188937.MA_4202; -.
DR EnsemblBacteria; AAM07548; AAM07548; MA_4202.
DR GeneID; 1476096; -.
DR KEGG; mac:MA_4202; -.
DR HOGENOM; CLU_074761_1_1_2; -.
DR InParanoid; Q8TIF0; -.
DR OrthoDB; 9937at2157; -.
DR PhylomeDB; Q8TIF0; -.
DR Proteomes; UP000002487; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR024654; Calcineurin-like_PHP_lpxH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR011152; Pesterase_MJ0912.
DR PANTHER; PTHR42850:SF2; BLL5683 PROTEIN; 1.
DR PANTHER; PTHR42850; METALLOPHOSPHOESTERASE; 1.
DR Pfam; PF12850; Metallophos_2; 1.
DR PIRSF; PIRSF000883; Pesterase_MJ0912; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839};
KW Reference proteome {ECO:0000313|Proteomes:UP000002487}.
FT DOMAIN 1..196
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF12850"
SQ SEQUENCE 233 AA; 26223 MW; C2814C1CCCDB3589 CRC64;
MKILLIADIH ANLEALQTVL EVPHDRVICL GDIVDYGPDP DKCIELLRKK NIPTLRGNHD
NAVAFKVDCQ CGYRYKHLSI ATREYTWGVL DQSQMEYLQK LPLVVREEID GKKLFLTHAS
PRSIFEYIKP ETPDEAIMAM LTDPMEPVDA EFLVVGHSHI PMIRELGALK IINPGSVGQP
RDGDTRAGCA VFDTETGETE LLRLEYDLEA VCAKIEERMP HADELAGILK RGY
//
