ID Q8TMF7_METAC Unreviewed; 314 AA.
AC Q8TMF7;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Transposase {ECO:0000313|EMBL:AAM06080.1};
GN OrderedLocusNames=MA_2701 {ECO:0000313|EMBL:AAM06080.1};
OS Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS C2A).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=188937 {ECO:0000313|EMBL:AAM06080.1, ECO:0000313|Proteomes:UP000002487};
RN [1] {ECO:0000313|EMBL:AAM06080.1, ECO:0000313|Proteomes:UP000002487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A
RC {ECO:0000313|Proteomes:UP000002487};
RX PubMed=11932238; DOI=10.1101/gr.223902;
RA Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA Cann I., Graham D.E., Grahame D.A., Guss A., Hedderich R., Ingram-Smith C.,
RA Kuettner C.H., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B.,
RA Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H.,
RA de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L.,
RA Paulsen I., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H.,
RA Lander E., Metcalf W.W., Birren B.;
RT "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT physiological diversity.";
RL Genome Res. 12:532-542(2002).
CC -!- FUNCTION: Involved in the transposition of the insertion sequence IS5.
CC {ECO:0000256|ARBA:ARBA00003544}.
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DR EMBL; AE010299; AAM06080.1; -; Genomic_DNA.
DR RefSeq; WP_011022661.1; NC_003552.1.
DR AlphaFoldDB; Q8TMF7; -.
DR STRING; 188937.MA_2701; -.
DR EnsemblBacteria; AAM06080; AAM06080; MA_2701.
DR GeneID; 1474594; -.
DR KEGG; mac:MA_2701; -.
DR HOGENOM; CLU_049873_1_1_2; -.
DR InParanoid; Q8TMF7; -.
DR OrthoDB; 148050at2157; -.
DR PhylomeDB; Q8TMF7; -.
DR Proteomes; UP000002487; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR GO; GO:0006313; P:DNA transposition; IEA:InterPro.
DR InterPro; IPR047959; Transpos_IS5.
DR InterPro; IPR002559; Transposase_11.
DR InterPro; IPR008490; Transposase_InsH_N.
DR NCBIfam; NF033581; transpos_IS5_4; 1.
DR PANTHER; PTHR35604; TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED; 1.
DR PANTHER; PTHR35604:SF2; TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED; 1.
DR Pfam; PF01609; DDE_Tnp_1; 1.
DR Pfam; PF05598; DUF772; 1.
PE 4: Predicted;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000002487}.
FT DOMAIN 51..122
FT /note="Transposase InsH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05598"
FT DOMAIN 139..302
FT /note="Transposase IS4-like"
FT /evidence="ECO:0000259|Pfam:PF01609"
FT REGION 147..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 314 AA; 36410 MW; 6017D3841522F1EE CRC64;
MKTFTDFALK EKYKHIQLVG DNLSELESLI GWKRFRLILE PMYVNKTASG GRPEADVIVM
FKMLVLQQWH GLSDPELEKH CIDRLSFRNF LGFPDYIPDS TTVWLFRKGI IDNEKEEEIW
DELQSQLDSH GLKIKKGMIQ DATFIHSDPE HAKADKPRGN EAKTRRSRDG TWTKKGSKLY
FGYKLHSIID RDYELIRRFK TTTALVHDSQ VDLSEENEVV YRDTGYFGAE AKGFAATMKR
AVRGHPLGIR DIIRNKRISL KRVPGERVYA VTKNVFSSGT VLVTTVERVN MKMLFTAFCY
NLHQLRTLKR KGVF
//
