ID Q8TXP0_METKA Unreviewed; 524 AA.
AC Q8TXP0;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Predicted RNA modification enzyme consisting of a 3-phosphoadenosine 5-phosphosulfate sulfotransferase fused to RNA-binding PUA domain {ECO:0000313|EMBL:AAM01836.1};
GN OrderedLocusNames=MK0621 {ECO:0000313|EMBL:AAM01836.1};
OS Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938).
OC Archaea; Euryarchaeota; Methanomada group; Methanopyri; Methanopyrales;
OC Methanopyraceae; Methanopyrus.
OX NCBI_TaxID=190192 {ECO:0000313|EMBL:AAM01836.1, ECO:0000313|Proteomes:UP000001826};
RN [1] {ECO:0000313|EMBL:AAM01836.1, ECO:0000313|Proteomes:UP000001826}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938
RC {ECO:0000313|Proteomes:UP000001826};
RX PubMed=11930014; DOI=10.1073/pnas.032671499;
RA Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A.,
RA Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G.,
RA Koonin E.V., Kozyavkin S.A.;
RT "The complete genome of hyperthermophile Methanopyrus kandleri AV19 and
RT monophyly of archaeal methanogens.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
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DR EMBL; AE009439; AAM01836.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8TXP0; -.
DR STRING; 190192.MK0621; -.
DR PaxDb; 190192-MK0621; -.
DR EnsemblBacteria; AAM01836; AAM01836; MK0621.
DR KEGG; mka:MK0621; -.
DR HOGENOM; CLU_026622_0_0_2; -.
DR InParanoid; Q8TXP0; -.
DR OrthoDB; 5817at2157; -.
DR Proteomes; UP000001826; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd01713; PAPS_reductase; 1.
DR CDD; cd07953; PUA; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR InterPro; IPR002500; PAPS_reduct.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004521; Uncharacterised_CHP00451.
DR NCBIfam; TIGR00451; unchar_dom_2; 1.
DR PANTHER; PTHR43196; SULFATE ADENYLYLTRANSFERASE SUBUNIT 2; 1.
DR PANTHER; PTHR43196:SF1; SULFATE ADENYLYLTRANSFERASE SUBUNIT 2; 1.
DR Pfam; PF01507; PAPS_reduct; 1.
DR Pfam; PF01472; PUA; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS50890; PUA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001826}.
FT DOMAIN 124..196
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
SQ SEQUENCE 524 AA; 59067 MW; ECB55EA482772EC0 CRC64;
MEKLPGKAPA YVCQECELVT PLRRCPECGE GTDPLRVTPP AELRPVGPGY LEFIREVLVE
EGLPADLVRD DELLLANRAP DLDYLDEIVA AEPVLALRYD LRKDRWTIVL KPEGARRLHE
LGGKSIEVDR GAAEAVREGK NLFAPGVTSA DDVEPGEWVV IEHGGRPVAF GRARMSGDEM
VRRNRGLAVE VRGAVEGSPT YFRGRDFEDV ARAHEEYVSE RLEEAVTFAR ENVSPSRTFA
SFSGGKDSLV TLVVAAEAGV ERALFVDTGM ELPETVEAAD RAAEAVGIDV EIVEGDPEIF
HRVTEALLPP SRDNRWCTLA AKLTPVTRYV RSEFGRGCYT LVGVRRYESE ARSERGRVWD
SDAVPGQVNV APIFDWSSLD VWLCVHSKDL PYNPLYDEGF DRIGCYMCPA SKVGDFRLSE
RVHPELWEGW METLERYRER HGLPRDWLRY HVWRWLRPEG EIRKVASEES LRWGERVLGR
WREVPPEEAA RGFRRECPGC GYCGAVGSNR CEILEASLRR VFGR
//
