ID Q8UZG2_9GAMA Unreviewed; 406 AA.
AC Q8UZG2;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=BBRF3 {ECO:0000313|EMBL:AAK95449.1};
OS Macacine gammaherpesvirus 4 (Rhesus lymphocryptovirus).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Orthoherpesviridae; Gammaherpesvirinae; Lymphocryptovirus;
OC Lymphocryptovirus macacinegamma4.
OX NCBI_TaxID=45455 {ECO:0000313|EMBL:AAK95449.1, ECO:0000313|Proteomes:UP000201521};
RN [1] {ECO:0000313|EMBL:AAK95449.1, ECO:0000313|Proteomes:UP000201521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LCL8664 {ECO:0000313|EMBL:AAK95449.1,
RC ECO:0000313|Proteomes:UP000201521};
RX PubMed=8892903;
RA Franken M., Devergne O., Rosenzweig M., Annis B., Kieff E., Wang F.;
RT "Comparative analysis identifies conserved tumor necrosis factor receptor-
RT associated factor 3 binding sites in the human and simian Epstein-Barr
RT virus oncogene LMP1.";
RL J. Virol. 70:7819-7826(1996).
RN [2] {ECO:0000313|EMBL:AAK95449.1, ECO:0000313|Proteomes:UP000201521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LCL8664 {ECO:0000313|EMBL:AAK95449.1,
RC ECO:0000313|Proteomes:UP000201521};
RX PubMed=10482645;
RA Rivailler P., Quink C., Wang F.;
RT "Strong selective pressure for evolution of an Epstein-Barr virus LMP2B
RT homologue in the rhesus lymphocryptovirus.";
RL J. Virol. 73:8867-8872(1999).
RN [3] {ECO:0000313|EMBL:AAK95449.1, ECO:0000313|Proteomes:UP000201521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LCL8664 {ECO:0000313|EMBL:AAK95449.1,
RC ECO:0000313|Proteomes:UP000201521};
RX PubMed=10970361;
RA Rao P., Jiang H., Wang F.;
RT "Cloning of the rhesus lymphocryptovirus viral capsid antigen and Epstein-
RT Barr virus-encoded small RNA homologues and use in diagnosis of acute and
RT persistent infections.";
RL J. Clin. Microbiol. 38:3219-3225(2000).
RN [4] {ECO:0000313|EMBL:AAK95449.1, ECO:0000313|Proteomes:UP000201521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LCL8664 {ECO:0000313|EMBL:AAK95449.1,
RC ECO:0000313|Proteomes:UP000201521};
RX PubMed=10846073; DOI=10.1128/JVI.74.13.5921-5932.2000;
RA Jiang H., Cho Y.G., Wang F.;
RT "Structural, functional, and genetic comparisons of Epstein-Barr virus
RT nuclear antigen 3A, 3B, and 3C homologues encoded by the rhesus
RT lymphocryptovirus.";
RL J. Virol. 74:5921-5932(2000).
RN [5] {ECO:0000313|EMBL:AAK95449.1, ECO:0000313|Proteomes:UP000201521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LCL8664 {ECO:0000313|EMBL:AAK95449.1,
RC ECO:0000313|Proteomes:UP000201521};
RX PubMed=11739708; DOI=10.1128/JVI.76.1.421-426.2002;
RA Rivailler P., Jiang H., Cho Y.G., Quink C., Wang F.;
RT "Complete nucleotide sequence of the rhesus lymphocryptovirus: genetic
RT validation for an Epstein-Barr virus animal model.";
RL J. Virol. 76:421-426(2002).
CC -!- FUNCTION: Envelope glycoprotein important for virion assembly and
CC egress. Plays a role in the correct incorporation of gH-gL into virion
CC membrane. Directs the glycoprotein N (gN) to the host trans-Golgi
CC network. {ECO:0000256|ARBA:ARBA00003017}.
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DR EMBL; AY037858; AAK95449.1; -; Genomic_DNA.
DR RefSeq; YP_067982.1; NC_006146.1.
DR GeneID; 2949740; -.
DR KEGG; vg:2949740; -.
DR OrthoDB; 7915at10239; -.
DR Proteomes; UP000201521; Genome.
DR GO; GO:0044175; C:host cell endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044178; C:host cell Golgi membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0044201; C:host cell nuclear inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0019031; C:viral envelope; IEA:UniProtKB-UniRule.
DR GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR HAMAP; MF_04035; HSV_GM; 1.
DR InterPro; IPR000785; Herpes_glycop_M.
DR Pfam; PF01528; Herpes_glycop; 1.
DR PRINTS; PR00333; HSVINTEGRLMP.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 18..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 346..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 406 AA; 45653 MW; 73E42003283FEC2C CRC64;
MKSSKNDTFV YKIWVKTLVV YFVMFVMSAV VPITAMFPDL GYPCYFNALV DYGALNLTQY
NTAHHLTPML YLEPPEMFVY ITLVFIVDCV AFIYYACGEV ALIKARRKVS GLTDLSAWVS
AVGSPTVLFL AILKLWSIQV FIQVLSYKHV FLSAFVYFLH FLASVLHACA CVTRFSPVWV
VKAQDNSIPQ DTFLWQVVFY LKPVVSNLYL GCLALETLVF SLSVFLALGN SFYFMVGDMV
LGAVNLFLIL PIFWYVLTEV WLASFLRHNF GFYCGMFIAS IILILPLVRY EAVFVSAKLH
TTVAINVAII PILCSVALLV RICRIFKTMR QGTDYVPISE TVELELEPTT RPRTRSSSLR
GGNGRRSSTS SSSSRSSSKR QRTVSAQAHV PSVLPMTSDS EDEIFP
//
