ID Q8VM94_RHOFA Unreviewed; 323 AA.
AC Q8VM94; A0A143QQK6;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE RecName: Full=RNA polymerase sigma factor {ECO:0000256|RuleBase:RU362124};
GN Name=rofB {ECO:0000313|EMBL:CAC83730.1};
GN Synonyms=sigB {ECO:0000313|EMBL:AMY25066.1};
GN ORFNames=A3Q41_03780 {ECO:0000313|EMBL:AMY25066.1}, CH298_23345
GN {ECO:0000313|EMBL:OZF11090.1};
OS Rhodococcus fascians.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=1828 {ECO:0000313|EMBL:CAC83730.1};
RN [1] {ECO:0000313|EMBL:CAC83730.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=D188 {ECO:0000313|EMBL:CAC83730.1};
RA Rincon J.;
RL Thesis (2000), Department of Ecology, Genetics and Microbiology, University
RL of Leon, Leon, Spain.
RN [2] {ECO:0000313|EMBL:CAC83730.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=D188 {ECO:0000313|EMBL:CAC83730.1};
RA Rincon J., Pisabarro A., Martin J.F.;
RT "Analysis of two sigma factor genes located in a 12 kb region of the
RT chromosome of the plant pathogen Rhodococcus fascians.";
RL Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AMY25066.1, ECO:0000313|Proteomes:UP000076038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBTS2 {ECO:0000313|EMBL:AMY25066.1,
RC ECO:0000313|Proteomes:UP000076038};
RX PubMed=27284129;
RA Stamler R.A., Vereecke D., Zhang Y., Schilkey F., Devitt N., Randall J.J.;
RT "Complete Genome and Plasmid Sequences for Rhodococcus fascians D188 and
RT Draft Sequences for Rhodococcus Isolates PBTS 1 and PBTS 2.";
RL Genome Announc. 4:0-0(2016).
RN [4] {ECO:0000313|Proteomes:UP000076038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBTS2 {ECO:0000313|Proteomes:UP000076038};
RA Stamer R., Vereecke D., Zhang Y., Schilkey F., Devitt N., Randall J.;
RT "Complete Genome and Plasmid Sequences for Rhodococcus fascians D188 and
RT Draft Sequences for Rhodococcus spp. Isolates PBTS 1 and PBTS 2.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:AMY25066.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PBTS2 {ECO:0000313|EMBL:AMY25066.1};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:OZF11090.1, ECO:0000313|Proteomes:UP000216662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=14-2632-D2 {ECO:0000313|EMBL:OZF11090.1,
RC ECO:0000313|Proteomes:UP000216662};
RA Savory E.A., Fuller S.L., Weisberg A.J., Thomas W.J., Gordon M.I.,
RA Stevens D.M., Creason A.L., Belcher M.S., Wiseman M., Putnam M.L.,
RA Grunwald N.J., Chang J.H.;
RT "Evolutionary transitions between beneficial and phytopathogenic
RT Rhodococcus challenge disease management.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. {ECO:0000256|RuleBase:RU362124}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family.
CC {ECO:0000256|RuleBase:RU362124}.
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DR EMBL; CP015220; AMY25066.1; -; Genomic_DNA.
DR EMBL; AJ308412; CAC83730.1; -; Genomic_DNA.
DR EMBL; NPFT01000022; OZF11090.1; -; Genomic_DNA.
DR RefSeq; WP_027496878.1; NZ_NPFU01000018.1.
DR STRING; 1443905.GCA_000761075_02607; -.
DR GeneID; 29798005; -.
DR KEGG; rhs:A3Q41_03780; -.
DR PATRIC; fig|1653479.3.peg.3834; -.
DR PATRIC; fig|1828.17.peg.2098; -.
DR eggNOG; COG0568; Bacteria.
DR OrthoDB; 9809557at2; -.
DR Proteomes; UP000076038; Chromosome.
DR Proteomes; UP000216662; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd06171; Sigma70_r4; 1.
DR Gene3D; 1.10.601.10; RNA Polymerase Primary Sigma Factor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007624; RNA_pol_sigma70_r3.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30603; RNA POLYMERASE SIGMA FACTOR RPO; 1.
DR PANTHER; PTHR30603:SF47; RNA POLYMERASE SIGMA FACTOR SIGF, CHLOROPLASTIC; 1.
DR Pfam; PF00140; Sigma70_r1_2; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04539; Sigma70_r3; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
DR PROSITE; PS00715; SIGMA70_1; 1.
DR PROSITE; PS00716; SIGMA70_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU362124};
KW Reference proteome {ECO:0000313|Proteomes:UP000076038};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU362124}.
FT DOMAIN 114..127
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00715"
FT DOMAIN 283..309
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00716"
SQ SEQUENCE 323 AA; 36091 MW; F5E148B3E9197BB8 CRC64;
MTSPSTTIRP RPTDADLDAQ SPAADLVRVY LNGIGRTALL TAEEEVDLAK RIEAGLYAKQ
VLENTKRLSA VKKRNLAIIV RDGSAARSHL LEANLRLVVS LAKRYTGRGM PLLDLIQEGN
LGLIRAMEKF DYAKGFKFST YATWWIRQAI TRGMADQSRT IRLPVHLVEQ VNKLARIKRE
LHQQLGREAT DEELSSESGI AVEKIADLLD HSRDPVSLDM PVGSDEEAPL GDFIEDSEAT
SAENAVIAGL LHSDVRVVLG TLDEREQQVI RLRYGLDDGQ PRTLDQIGKL FGLSRERVRQ
IEREVMVKLR QGDRAEKLRS YAS
//
