ID Q8VTB7_HELPX Unreviewed; 343 AA.
AC Q8VTB7;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Type II DNA modification enzyme {ECO:0000313|EMBL:AAL37471.1};
OS Helicobacter pylori (Campylobacter pylori).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=210 {ECO:0000313|EMBL:AAL37471.1};
RN [1] {ECO:0000313|EMBL:AAL37471.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CR38 {ECO:0000313|EMBL:AAL37471.1};
RX PubMed=12427957;
RA Chanto G., Occhialini A., Gras N., Alm R.A., Megraud F., Marais A.;
RT "Identification of strain-specific genes located outside the plasticity
RT zone in nine clinical isolates of Helicobacter pylori.";
RL Microbiology 148:3671-3680(2002).
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
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DR EMBL; AF328924; AAL37471.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8VTB7; -.
DR REBASE; 6501; M.HpyCR38ORFCP.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR002295; N4/N6-MTase_EcoPI_Mod-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13370:SF32; DNA ADENINE METHYLTRANSFERASE YHDJ; 1.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PRINTS; PR00506; D21N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 27..318
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
SQ SEQUENCE 343 AA; 39444 MW; D7C6D220CBB00321 CRC64;
MQNLLIQAEN AIALLFLLND KNLKGKIDLI YIDPPFATNN HFTITNGRAT TISNSKNGDI
AYSDKVVGMD FIEFLKQRLV LLKELLSEQG SIYVHTDCKI GHYVKVMLDE IFGIQNFINE
ITRIKCNPKN FKRMGYGNIK DMILFYSKGK NPIFNEPKIP YTPQDLEKRF PKIDKDKRRY
TTVPIHAPGE VESGECSKAF KGMLPPKGRH WRTDIATLER WDKEGLIEYS NNNNPRKKIY
ALEQVGKRVQ DIWEFKDPQY PSYPTEKNAQ LLDLIIKTSS NKDSIVLDCF CGSGTTLKSA
FLLQRKFIGI DNSNLAIQAC KNKLETITKD LFVSQNFYDF LVF
//
