ID Q8WP60_DROSI Unreviewed; 335 AA.
AC Q8WP60;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 24-JAN-2024, entry version 80.
DE SubName: Full=Gelsolin {ECO:0000313|EMBL:AAL31728.1};
DE Flags: Fragment;
GN Name=Gel {ECO:0000313|EMBL:AAL31728.1};
OS Drosophila simulans (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7240 {ECO:0000313|EMBL:AAL31728.1};
RN [1] {ECO:0000313|EMBL:AAL31728.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11801748;
RA Begun D.J.;
RT "Protein variation in Drosophila simulans, and comparison of genes from
RT centromeric versus noncentromeric regions of chromosome 3.";
RL Mol. Biol. Evol. 19:201-203(2002).
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DR EMBL; AY052176; AAL31728.1; -; Genomic_DNA.
DR EMBL; AY052177; AAL31729.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8WP60; -.
DR ChiTaRS; Bsg; fly.
DR GO; GO:0005884; C:actin filament; IEA:EnsemblMetazoa.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblMetazoa.
DR GO; GO:0005576; C:extracellular region; IEA:EnsemblMetazoa.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR CDD; cd11291; gelsolin_S6_like; 1.
DR Gene3D; 3.40.20.10; Severin; 3.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR007122; Villin/Gelsolin.
DR PANTHER; PTHR11977:SF123; GELSOLIN; 1.
DR PANTHER; PTHR11977; VILLIN; 1.
DR Pfam; PF00626; Gelsolin; 2.
DR PRINTS; PR00597; GELSOLIN.
DR SMART; SM00262; GEL; 3.
DR SUPFAM; SSF55753; Actin depolymerizing proteins; 3.
PE 4: Predicted;
FT DOMAIN 141..209
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT DOMAIN 248..322
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAL31728.1"
FT NON_TER 335
FT /evidence="ECO:0000313|EMBL:AAL31728.1"
SQ SEQUENCE 335 AA; 37380 MW; C8BCC7FCE7092041 CRC64;
GRAFGFMPDH GQNGIEIITQ YVAKPGSDEI VVSTVPFDEK LPLLGFASYV LTYNYEANNG
DTGRLTYVWH GVNASAAAKK RAFEEGLVGA KDGLLVQTNQ GHEPRHFYKI FKGKLLTSFT
ALPVTAQLFR IRGTVESDVH ASEVAADSSS LASSDAFALH SGKSHKIYIW NGLGASAFEK
QAAVDRFSDY WDDVELEQVE EGAEPDEFWE ELNGEGQYDR SLGDDGAPLL ESRLFHCLLS
SGGLLKVEEV AQYEQEDLDS DDIMLLDAGD EIYLWVGYGV SEEENAKLLD MAKLYIHLEP
TARSFDTVSI IRVPQGKEPR VFKRMFPNWD DNYWQ
//
