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Database: UniProt
Entry: Q8X5P3
LinkDB: Q8X5P3
Original site: Q8X5P3 
ID   DCTR_ECO57              Reviewed;         176 AA.
AC   Q8X5P3; Q7AA19;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   14-MAY-2014, entry version 74.
DE   RecName: Full=HTH-type transcriptional regulator DctR;
GN   Name=dctR; OrderedLocusNames=Z4909, ECs4378;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [3]
RP   FUNCTION.
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=12704134; DOI=10.1128/IAI.71.5.2598-2606.2003;
RA   Tatsuno I., Nagano K., Taguchi K., Rong L., Mori H., Sasakawa C.;
RT   "Increased adherence to Caco-2 cells caused by disruption of the yhiE
RT   and yhiF genes in enterohemorrhagic Escherichia coli O157:H7.";
RL   Infect. Immun. 71:2598-2606(2003).
CC   -!- FUNCTION: May act as a transcriptional regulator of dctA (By
CC       similarity). Could be involved in the regulation of the genes
CC       coding for the type III secretion system in enterohaemorragic
CC       strains.
CC   -!- INDUCTION: By acidic conditions. Could be induced by EvgA via the
CC       induction of YdeO (By similarity).
CC   -!- SIMILARITY: Contains 1 HTH luxR-type DNA-binding domain.
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DR   EMBL; AE005174; AAG58639.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB37801.1; -; Genomic_DNA.
DR   PIR; B91176; B91176.
DR   PIR; C86022; C86022.
DR   RefSeq; NP_290078.1; NC_002655.2.
DR   RefSeq; NP_312405.1; NC_002695.1.
DR   ProteinModelPortal; Q8X5P3; -.
DR   SMR; Q8X5P3; 119-176.
DR   STRING; 155864.Z4909; -.
DR   EnsemblBacteria; AAG58639; AAG58639; Z4909.
DR   EnsemblBacteria; BAB37801; BAB37801; BAB37801.
DR   GeneID; 915765; -.
DR   GeneID; 961181; -.
DR   KEGG; ece:Z4909; -.
DR   KEGG; ecs:ECs4378; -.
DR   PATRIC; 18358329; VBIEscCol44059_4331.
DR   eggNOG; COG2771; -.
DR   HOGENOM; HOG000125804; -.
DR   OMA; APEADIM; -.
DR   OrthoDB; EOG6KWXXP; -.
DR   BioCyc; ECOL386585:GJFA-4344-MONOMER; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   Pfam; PF00196; GerE; 1.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; DNA-binding; Transcription;
KW   Transcription regulation.
FT   CHAIN         1    176       HTH-type transcriptional regulator DctR.
FT                                /FTId=PRO_0000184147.
FT   DOMAIN      109    174       HTH luxR-type.
FT   DNA_BIND    133    152       H-T-H motif (By similarity).
SQ   SEQUENCE   176 AA;  20451 MW;  F1E35D5A3B82BB8C CRC64;
     MFLIITRDTM FFTAMKNILS KGNVVHIQNE EEIDVMLHQN AFVIIDTLMN NVFHSNFLTQ
     IERLKPVHVI IFSPFNIKRC LGKVPVTFVP RTITIIDFVA LINGSYCSVP EANVSLSRKQ
     HQVLSCIANQ MTTEDILEKL KISLKTFYCH KHNIMMILNL KRINELVRHQ HIDYLV
//
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