ID Q8Y414_LISMO Unreviewed; 343 AA.
AC Q8Y414;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 138.
DE SubName: Full=Lmo2663 protein {ECO:0000313|EMBL:CAD00876.1};
GN OrderedLocusNames=lmo2663 {ECO:0000313|EMBL:CAD00876.1};
OS Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX NCBI_TaxID=169963 {ECO:0000313|EMBL:CAD00876.1, ECO:0000313|Proteomes:UP000000817};
RN [1] {ECO:0000313|EMBL:CAD00876.1, ECO:0000313|Proteomes:UP000000817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-679 / EGD-e {ECO:0000313|Proteomes:UP000000817};
RX PubMed=11679669; DOI=10.1126/science.1063447;
RA Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.D.,
RA Fsihi H., Portillo F.G., Garrido P., Gautier L., Goebel W., Gomez-Lopez N.,
RA Hain T., Hauf J., Jackson D., Jones L.M., Kaerst U., Kreft J., Kuhn M.,
RA Kunst F., Kurapkat G., Madueno E., Maitournam A., Vicente J.M., Ng E.,
RA Nedjari H., Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.C.,
RA Purcell R., Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A.,
RA Vazquez-Boland J.A., Voss H., Wehland J., Cossart P.;
RT "Comparative genomics of Listeria species.";
RL Science 294:849-852(2001).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
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DR EMBL; AL591984; CAD00876.1; -; Genomic_DNA.
DR PIR; AF1407; AF1407.
DR RefSeq; NP_466185.1; NC_003210.1.
DR RefSeq; WP_003733054.1; NZ_CP023861.1.
DR AlphaFoldDB; Q8Y414; -.
DR STRING; 169963.gene:17595380; -.
DR PaxDb; 169963-lmo2663; -.
DR EnsemblBacteria; CAD00876; CAD00876; CAD00876.
DR GeneID; 984376; -.
DR KEGG; lmo:lmo2663; -.
DR PATRIC; fig|169963.11.peg.2729; -.
DR eggNOG; COG1063; Bacteria.
DR HOGENOM; CLU_026673_11_0_9; -.
DR OrthoDB; 9770238at2; -.
DR PhylomeDB; Q8Y414; -.
DR BioCyc; LMON169963:LMO2663-MONOMER; -.
DR BioCyc; MetaCyc:MONOMER-124211; -.
DR Proteomes; UP000000817; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd08258; Zn_ADH4; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR PANTHER; PTHR43401:SF2; L-THREONINE 3-DEHYDROGENASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000817};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 10..341
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 343 AA; 37243 MW; 2901D0B0C60907B8 CRC64;
MKAVVKTNPG YDQMELKDVE EPQVYGDKVK IKVAFTGICG SDIHTFKGEY KNPTTPVTLG
HEFSGVVVEV GPDVTSIKVG DRVTSETTFE TCGECIYCKE HDYNLCSNRR GIGTQANGSF
AEFVLSREES CHVLDERISL EAAALTEPLA CCVHSALEKT TIRPDDTVLV FGPGPIGLLL
AQVVKAQGAT VIMAGITKDS DRLRLAKELG MDRIVDTLKE DLAEVVLGMT GGYGAERVFD
CSGAVPAVNQ GLPLTKKKGD FVQVGLFAEK KNAIDEESII QREIAYIGSR SQKPSSWILA
LDLLANGKID TDKMITKVYG LDDWREAFEA VMAGNEIKVL VKS
//
