ID Q8ZPJ7_SALTY Unreviewed; 811 AA.
AC Q8ZPJ7;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 139.
DE SubName: Full=Dimethyl sulfoxide reductase {ECO:0000313|EMBL:AAL20417.1};
DE EC=1.8.99.- {ECO:0000313|EMBL:AAL20417.1};
GN OrderedLocusNames=STM1498 {ECO:0000313|EMBL:AAL20417.1};
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287 {ECO:0000313|EMBL:AAL20417.1, ECO:0000313|Proteomes:UP000001014};
RN [1] {ECO:0000313|EMBL:AAL20417.1, ECO:0000313|Proteomes:UP000001014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720
RC {ECO:0000313|Proteomes:UP000001014};
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR EMBL; AE006468; AAL20417.1; -; Genomic_DNA.
DR RefSeq; NP_460458.1; NC_003197.2.
DR RefSeq; WP_000705294.1; NC_003197.2.
DR AlphaFoldDB; Q8ZPJ7; -.
DR STRING; 99287.STM1498; -.
DR PaxDb; 99287-STM1498; -.
DR GeneID; 1253016; -.
DR KEGG; stm:STM1498; -.
DR PATRIC; fig|99287.12.peg.1583; -.
DR HOGENOM; CLU_000422_13_3_6; -.
DR OMA; HYSDYST; -.
DR PhylomeDB; Q8ZPJ7; -.
DR BioCyc; SENT99287:STM1498-MONOMER; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IBA:GO_Central.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0009389; F:dimethyl sulfoxide reductase activity; IEA:InterPro.
DR GO; GO:0009055; F:electron transfer activity; IBA:GO_Central.
DR GO; GO:0030151; F:molybdenum ion binding; IBA:GO_Central.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0009061; P:anaerobic respiration; IBA:GO_Central.
DR CDD; cd02794; MopB_CT_DmsA-EC; 1.
DR CDD; cd02770; MopB_DmsA-EC; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.12440; -; 2.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR011888; Anaer_DMSO_reductase.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR InterPro; IPR027467; MopterinOxRdtase_cofactor_BS.
DR InterPro; IPR006311; TAT_signal.
DR NCBIfam; TIGR02166; dmsA_ynfE; 1.
DR NCBIfam; NF041884; selenate_YnfF; 1.
DR PANTHER; PTHR43742:SF1; DIMETHYL SULFOXIDE REDUCTASE CHAIN YNFF-RELATED; 1.
DR PANTHER; PTHR43742; TRIMETHYLAMINE-N-OXIDE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00551; MOLYBDOPTERIN_PROK_1; 1.
DR PROSITE; PS00932; MOLYBDOPTERIN_PROK_3; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:AAL20417.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001014};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 56..117
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
FT REGION 790..811
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 811 AA; 89774 MW; 41776CAEAD9BD6C6 CRC64;
MKITNPEALM AASLSRRSLV KTSAIGSLAL ASSAFTLPFS RIAHAAADLA SGNVAEKAVW
SSCTVNCGSR CLLRLHVKDD TVYWVESDTT GNDEYGNHQV RACLRGRSIR RRMNHPDRLK
YPMKRVGKRG EGKFERISWD EALDTIGDNL KRILKDYGNE AVHVLYGTGV DGGNITNSNV
PYRLMNACGG YLSRYGSYST AQISAAMSYM FGGNDGNSPD DIANTKLVVM FGNNPAETRM
SGGGVTYYVE QARERSNARM IVIDPRYNDT AAGREDEWLP IRPGTDGALA AAIAWVLITE
DLIDKPFLDK YCIGYDETTL PASAPRNAHY KAYILGQGDD GIAKTPQWAA QITSIPAEKI
IQLAREIGSA KPAYICQGWG PQRHSNGEQT ARAIAMLSVL TGNVGINGGN SGVREGTWDL
GVEWFSMLEN PVKTQISVFT WTDAIDHGAE MTATRDGVRG KDKLDVPIKF LWCYASNTLI
NQHGDIAHTH EVLQDDSKCE MIVGIEHFMT ASAKYCDILL PDLMPTEQED LISHESAGNM
GYVILGQPAT SPKFERKPIY WTLSEVAKRL GPDVYQTFTE GRTQHEWVKY LHAKTKARNP
EMPDYEEMKQ TGIFKKKCPE EHYVAFRAFR EDPAANPLKT PSGKIEIYSE RLATLANTWE
LKKDEIIHPL PAYTPGFDGW DDPLRQRYPL QLTGFHYKAR THSSYGNIDI LQQACPQEIW
INPIDAQARG IQHGDTVRVF NQNGEMLIPA KVTPRILPGV TAIGQGAWLN ADMFGDKVDR
GGSINILTSH RPSPLAKGNP SHSNLVQVEK A
//
