ID Q8ZRF1_SALTY Unreviewed; 403 AA.
AC Q8ZRF1;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 127.
DE SubName: Full=Permease {ECO:0000313|EMBL:AAL19336.1};
GN OrderedLocusNames=STM0382 {ECO:0000313|EMBL:AAL19336.1};
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287 {ECO:0000313|EMBL:AAL19336.1, ECO:0000313|Proteomes:UP000001014};
RN [1] {ECO:0000313|EMBL:AAL19336.1, ECO:0000313|Proteomes:UP000001014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720
RC {ECO:0000313|Proteomes:UP000001014};
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE006468; AAL19336.1; -; Genomic_DNA.
DR RefSeq; NP_459377.1; NC_003197.2.
DR RefSeq; WP_000446768.1; NC_003197.2.
DR AlphaFoldDB; Q8ZRF1; -.
DR STRING; 99287.STM0382; -.
DR PaxDb; 99287-STM0382; -.
DR GeneID; 1251901; -.
DR KEGG; stm:STM0382; -.
DR PATRIC; fig|99287.12.peg.405; -.
DR HOGENOM; CLU_001265_57_3_6; -.
DR OMA; ATMYIAL; -.
DR PhylomeDB; Q8ZRF1; -.
DR BioCyc; SENT99287:STM0382-MONOMER; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17391; MFS_MdtG_MDR_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR001958; Tet-R_TetA/multi-R_MdtG-like.
DR PANTHER; PTHR43414; MULTIDRUG RESISTANCE PROTEIN MDTG; 1.
DR PANTHER; PTHR43414:SF6; MULTIDRUG RESISTANCE PROTEIN MDTG; 1.
DR Pfam; PF07690; MFS_1; 1.
DR PRINTS; PR01035; TCRTETA.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001014};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..239
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..395
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 403 AA; 43521 MW; 314310E2CC63CED0 CRC64;
MESWKVNLIS VWFGCFFTGL AISQILPFLP LYISQLGVSS HEALSMWSGL TFSITFLISA
IVSPMWGSLA DRKGRKLMLL RASLGMAIAI LLQAFATHVW QLFLLRGIMG LTSGYIPNAM
ALVASQVPRE RSGWALSTLS TAQISGVIGG PLMGGFVADH IGLRAVFLIT AMLLVVSFLV
TLFLIKEGVR PVIKKSERLS GKAVFASLPY PALVISLFFT TMVIQLCNGS ISPILALFIK
SMMPDSNNIA FLSGLIASVP GISALISAPR LGKLGDRIGT ERILMATLIC AVLLFFAMSW
VTTPFQLGLL RFLLGFADGA MLPAVQTLLV KYSSDQITGR IFGYNQSFMY LGNVVGPLMG
ATVSAMAGFR WVFIATAAIV LINIGQLTLA LRRRRNAQKA KGQ
//
