ID Q8ZW43_PYRAE Unreviewed; 174 AA.
AC Q8ZW43;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 24-JAN-2024, entry version 91.
DE SubName: Full=Aerolysin, part 1, authentic frameshift {ECO:0000313|EMBL:AAL63859.1};
GN OrderedLocusNames=PAE1982 {ECO:0000313|EMBL:AAL63859.1};
OS Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP
OS 104966 / NBRC 100827 / IM2).
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Pyrobaculum.
OX NCBI_TaxID=178306 {ECO:0000313|EMBL:AAL63859.1, ECO:0000313|Proteomes:UP000002439};
RN [1] {ECO:0000313|EMBL:AAL63859.1, ECO:0000313|Proteomes:UP000002439}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 /
RC IM2 {ECO:0000313|Proteomes:UP000002439};
RX PubMed=11792869; DOI=10.1073/pnas.241636498;
RA Fitz-Gibbon S.T., Ladner H., Kim U.J., Stetter K.O., Simon M.I.,
RA Miller J.H.;
RT "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum
RT aerophilum.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073}.
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DR EMBL; AE009441; AAL63859.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8ZW43; -.
DR STRING; 178306.PAE1982; -.
DR EnsemblBacteria; AAL63859; AAL63859; PAE1982.
DR KEGG; pai:PAE1982; -.
DR PATRIC; fig|178306.9.peg.1463; -.
DR eggNOG; arCOG00702; Archaea.
DR HOGENOM; CLU_1536718_0_0_2; -.
DR InParanoid; Q8ZW43; -.
DR Proteomes; UP000002439; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR Pfam; PF00082; Peptidase_S8; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000002439}.
FT DOMAIN 113..149
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
SQ SEQUENCE 174 AA; 19636 MW; 205D06289757712A CRC64;
MAALVAFLQA ARIVVGYVDS PPTEALKELN KTGDIKIIKH LKEIKAIVLN IPDNKTEKLK
EKLKGVRYIE EDGVAYAFGF SNYTDVQWNV KMINAPRVWD AYFLTFGDAA FGYGVKVAVL
DTGIDYKHPE LSGKVVYCIN TLGNTLYKGT NLRKCADRKW PRHACSWDNS RFVE
//
