ID Q91T43_9ENTO Unreviewed; 878 AA.
AC Q91T43;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Genome polyprotein {ECO:0000256|ARBA:ARBA00020107};
DE Flags: Fragment;
OS Poliovirus 3.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Picornaviridae; Ensavirinae; Enterovirus; Enterovirus C.
OX NCBI_TaxID=12086 {ECO:0000313|EMBL:AAK38585.1};
RN [1] {ECO:0000313|EMBL:AAK38585.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Sabin strain 1F9 {ECO:0000313|EMBL:AAK38585.1};
RX PubMed=11277698; DOI=10.1006/viro.2000.0786;
RA Buttinelli G., Ruggeri F.M., Marturano J., Novello F., Donati V., Fiore L.;
RT "Antigenic sites of poliovirus type 3 eliciting IgA monoclonal antibodies
RT in orally immunized mice.";
RL Virology 281:265-271(2001).
CC -!- SUBUNIT: Interacts with capsid protein VP1 and capsid protein VP3 to
CC form heterotrimeric protomers. {ECO:0000256|ARBA:ARBA00011474}.
CC -!- SIMILARITY: Belongs to the picornaviruses polyprotein family.
CC {ECO:0000256|ARBA:ARBA00008303}.
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DR EMBL; AF334953; AAK38585.1; -; Genomic_RNA.
DR PIR; S09387; S09387.
DR MEROPS; N08.001; -.
DR GO; GO:0019028; C:viral capsid; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0044694; P:pore-mediated entry of viral genome into host cell; IEA:UniProtKB-KW.
DR GO; GO:0039657; P:suppression by virus of host gene expression; IEA:UniProtKB-KW.
DR GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
DR CDD; cd00205; rhv_like; 3.
DR Gene3D; 2.60.120.20; -; 3.
DR InterPro; IPR003138; Pico_P1A.
DR InterPro; IPR001676; Picornavirus_capsid.
DR InterPro; IPR033703; Rhv-like.
DR InterPro; IPR029053; Viral_coat.
DR Pfam; PF02226; Pico_P1A; 1.
DR Pfam; PF00073; Rhv; 3.
DR SUPFAM; SSF88633; Positive stranded ssRNA viruses; 2.
PE 3: Inferred from homology;
KW Capsid protein {ECO:0000256|ARBA:ARBA00022561};
KW Eukaryotic host gene expression shutoff by virus
KW {ECO:0000256|ARBA:ARBA00023247};
KW Eukaryotic host translation shutoff by virus
KW {ECO:0000256|ARBA:ARBA00022809};
KW Host gene expression shutoff by virus {ECO:0000256|ARBA:ARBA00022995};
KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022581};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Myristate {ECO:0000256|ARBA:ARBA00022707};
KW Pore-mediated penetration of viral genome into host cell
KW {ECO:0000256|ARBA:ARBA00023255};
KW Viral attachment to host cell {ECO:0000256|ARBA:ARBA00022804};
KW Viral penetration into host cytoplasm {ECO:0000256|ARBA:ARBA00022595};
KW Virion {ECO:0000256|ARBA:ARBA00022561};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 93..306
FT /note="Picornavirus capsid"
FT /evidence="ECO:0000259|Pfam:PF00073"
FT DOMAIN 369..527
FT /note="Picornavirus capsid"
FT /evidence="ECO:0000259|Pfam:PF00073"
FT DOMAIN 634..792
FT /note="Picornavirus capsid"
FT /evidence="ECO:0000259|Pfam:PF00073"
FT NON_TER 878
FT /evidence="ECO:0000313|EMBL:AAK38585.1"
SQ SEQUENCE 878 AA; 97307 MW; 5DBD25F4DBE274DD CRC64;
MGAQVSSQKV GAHENSNRAY GGSTINYTTI NYYKDSASNA ASKQDYSQDP SKFTEPLKDV
LIKTAPALNS PNVEACGYSD RVLQLTLGNS TITTQEAANS VVAYGRWPEF IRDDEANPVD
QPTEPDVATC RFYTLDTVMW GKESKGWWWK LPDALRDMGL FGQNMYYHYL GRSGYTVHVQ
CNASKFHQGA LGVFAIPEYC LAGDSDKQRY TSYANANPGE RGGKFYSQFN KDNAVTSPKR
EFCPVDYLLG CGVLLGNAFV YPHQIINLRT NNSATIVLPY VNALAIDSMV KHNNWGIAIL
PLSPLDFAQD SSVEIPITVT IAPMCSEFNG LRNVTAPKFQ GLPVLNTPGS NQYLTSDNHQ
SPCAIPEFDV TPPIDIPGEV KNMMELAEID TMIPLNLEGT KRNTMDMYRV TLSDSADLSQ
PILCLSLSPA FDPRLSHTML GEVLNYYTHW AGSLKFTFLF CGSMMATGKI LVAYAPPGAQ
PPTSRKEAML GTHVIWDLGL QSSCTMVVPW ISNVTYRQTT QDSFTEGGYI SMFYQTRIVV
PQSTPKSMSM LGFVSACNDF SVRLLRDTTH ISQSVLPQGI EDLISEVAQG ALTLSLPKQQ
DSLPDTKASG PAHSKEVPAL TAVETGATNP LAPSDTVQTR HVVQRRSRSE STIESFFARG
ACVAIIEVDN EQPTTRAQKL FAMWRITYKD TVQLRRMLEF FTYSRFDMEF TFVVTANFTN
ANNGHALNQV YQIMYIPPGA PTPKSWDDYT WQTSSNPSIF YTYGAAPARI SVPYVGLANA
YSHFYDGFAK VPLKTDANDQ IGDSLYSAMT VDDFGVLAVR VVNDHNPTKV TSKVRIYMKP
KHVRVWCPRP PRAVPYYGPG VDYRNNLDPL SEKGLTTY
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