ID Q91Z68_MOUSE Unreviewed; 150 AA.
AC Q91Z68;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 22-FEB-2023, entry version 106.
DE SubName: Full=GAP3 {ECO:0000313|EMBL:AAL27031.1};
DE Flags: Fragment;
GN Name=Srgap3 {ECO:0000313|MGI:MGI:2152938};
GN Synonyms=Srgap2 {ECO:0000313|MGI:MGI:2152938};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAL27031.1};
RN [1] {ECO:0000313|EMBL:AAL27031.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11672528; DOI=10.1016/S0092-8674(01)00530-X;
RA Wong K., Ren X.R., Huang Y.Z., Xie Y., Liu G., Saito H., Tang H., Wen L.,
RA Brady-Kalnay S.M., Mei L., Wu J.Y., Xiong W.C., Rao Y.;
RT "Signal transduction in neuronal migration: roles of GTPase activating
RT proteins and the small GTPase Cdc42 in the Slit-Robo pathway.";
RL Cell 107:209-221(2001).
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DR EMBL; AY057899; AAL27031.1; -; mRNA.
DR RefSeq; NP_536696.4; NM_080448.4.
DR AlphaFoldDB; Q91Z68; -.
DR PeptideAtlas; Q91Z68; -.
DR DNASU; 259302; -.
DR GeneID; 259302; -.
DR KEGG; mmu:259302; -.
DR AGR; MGI:2152938; -.
DR CTD; 9901; -.
DR MGI; MGI:2152938; Srgap3.
DR BioGRID-ORCS; 259302; 3 hits in 79 CRISPR screens.
DR ChiTaRS; Srgap3; mouse.
DR Genevisible; Q91Z68; MM.
DR CDD; cd11955; SH3_srGAP1-3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR035648; srGAP1/2/3_SH3.
DR PANTHER; PTHR14166; SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR14166:SF8; SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 3; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR PRINTS; PR01887; SPECTRNALPHA.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 2: Evidence at transcript level;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 39..98
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 103..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAL27031.1"
FT NON_TER 150
FT /evidence="ECO:0000313|EMBL:AAL27031.1"
SQ SEQUENCE 150 AA; 16559 MW; 83A1A957D4D3BB04 CRC64;
EKCMAGGEEY CDSPHSEPGT IDEVDHDNGT EPHTSDEEVE QIEAIAKFDY VGRSPRELSF
KKGASLLLYH RASEDWWEGR HNGVDGLIPH QYIVVQDMDD AFSDSLSQKA DSEASSGPLL
DDKASSKNDL QSPTEHISDY GFGGVMGRVR
//
