ID Q92MT9_RHIME Unreviewed; 853 AA.
AC Q92MT9;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=Dimethylglycine dehydrogenase {ECO:0000313|EMBL:CAC47100.1};
DE EC=1.5.99.2 {ECO:0000313|EMBL:CAC47100.1};
GN ORFNames=SMc01987 {ECO:0000313|EMBL:CAC47100.1};
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834 {ECO:0000313|EMBL:CAC47100.1, ECO:0000313|Proteomes:UP000001976};
RN [1] {ECO:0000313|EMBL:CAC47100.1, ECO:0000313|Proteomes:UP000001976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021 {ECO:0000313|EMBL:CAC47100.1,
RC ECO:0000313|Proteomes:UP000001976};
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [2] {ECO:0000313|Proteomes:UP000001976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021 {ECO:0000313|Proteomes:UP000001976};
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL591688; CAC47100.1; -; Genomic_DNA.
DR RefSeq; NP_386627.1; NC_003047.1.
DR RefSeq; WP_010969994.1; NC_003047.1.
DR AlphaFoldDB; Q92MT9; -.
DR EnsemblBacteria; CAC47100; CAC47100; SMc01987.
DR GeneID; 61603978; -.
DR KEGG; sme:SMc01987; -.
DR PATRIC; fig|266834.11.peg.4015; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0665; Bacteria.
DR HOGENOM; CLU_007884_11_2_5; -.
DR OrthoDB; 9804379at2; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:CAC47100.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001976}.
FT DOMAIN 9..382
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 385..441
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 443..722
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 790..836
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 853 AA; 95505 MW; 96DDDD18B88EDF50 CRC64;
MAEFPEKAKV VIVGLGGIVG ASIAHHLIER GWDDIVGIDK SGIPTDIGST AHASDFCYTT
SHDYLSVWTT QYSIDFFEKM GHYARIGGLE VARTGDHVWM EEIKRKLSSA KAFGTRAHYV
SPAEIKKLFP LIEEDQVMGG MFDPDAGLVV PRSQTVAGKL VDAAEKSGKL QIFGNTPATA
LLVENGRIKG VVTHRGTIMA DHVVVCAGIW GRLIAEMVGE DLPVMPVDHP LTFFGPYNEF
EGTGKEIGFP LLRDQGNSAY MRDTGDPKTT EGGQIEWGYY ETDNPRLCHP RDILEKHEAR
LSPSQRDLDM EQIIEPLERA MELTPILGEL GYNEGHSFNG LLQVSAAGGP SCGESQKVRG
LWYCVAIWVK DGPAYGKLIA DWMTDGRTHT DHASIDYARF YPHQLEEKFI EGRCFEAAQK
IYFPAVHPRE PYASGRNVKH SPFYEREKEL GGYFMELGGW ERAHGYAANE HLLEKYGNRI
PVRENEWDNR HFWRVSNAEH LAMSEDCGIV NLSHFHMVDI EGPDHVELLE WLCAAKIGGD
GNIGKGIYTH FLDDEGMVRA DFTVFRMADR CRLVNGADAG PRDFHYMRRV AEDRGLDVTI
TDVSEKFVTI GIWGPNARET LKKVVAEPAG LDPENFPFAS IKQIEIAGRP VSAFRISYVG
EQGWELHMKY EDGLAVWDAL RATGVMAFGV ETYANSRRME KSLRLQNADL LTHYNLIEAD
LARPKVKEAD FRGKAKHLEY KAREHQPAML CTLVMTENTD RNGVKRYPVG NLPVMDPETG
EVLVDELGRR SYTTSIAYGP TIGKNIALAY LPWSHCQVGR KLNVEYFAET YPVEVAGVGY
KPLYDPENLK PRT
//
