ID Q93377_CAEEL Unreviewed; 607 AA.
AC Q93377;
DT 01-FEB-1997, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 4.
DT 27-MAR-2024, entry version 152.
DE SubName: Full=LRRCT domain-containing protein {ECO:0000313|EMBL:CAB01867.4};
GN Name=lron-1 {ECO:0000313|EMBL:CAB01867.4,
GN ECO:0000313|WormBase:C44H4.1};
GN ORFNames=C44H4.1 {ECO:0000313|WormBase:C44H4.1}, CELE_C44H4.1
GN {ECO:0000313|EMBL:CAB01867.4};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAB01867.4, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAB01867.4, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAB01867.4,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284606; CAB01867.4; -; Genomic_DNA.
DR RefSeq; NP_510424.4; NM_078023.5.
DR AlphaFoldDB; Q93377; -.
DR SMR; Q93377; -.
DR STRING; 6239.C44H4.1.1; -.
DR EPD; Q93377; -.
DR PaxDb; 6239-C44H4-1; -.
DR PeptideAtlas; Q93377; -.
DR EnsemblMetazoa; C44H4.1.1; C44H4.1.1; WBGene00008093.
DR GeneID; 181553; -.
DR KEGG; cel:CELE_C44H4.1; -.
DR UCSC; C44H4.1; c. elegans.
DR AGR; WB:WBGene00008093; -.
DR WormBase; C44H4.1; CE44928; WBGene00008093; lron-1.
DR eggNOG; KOG0619; Eukaryota.
DR HOGENOM; CLU_461801_0_0_1; -.
DR InParanoid; Q93377; -.
DR OMA; CELRWYS; -.
DR OrthoDB; 5357459at2759; -.
DR PhylomeDB; Q93377; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00008093; Expressed in pharyngeal muscle cell (C elegans) and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR Pfam; PF13306; LRR_5; 1.
DR Pfam; PF13855; LRR_8; 3.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 10.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS51450; LRR; 4.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..607
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004319406"
FT TRANSMEM 522..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 431..484
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
SQ SEQUENCE 607 AA; 67509 MW; C6CFF2B3BEBB3A87 CRC64;
MRLLLFNLLI AGWVYSQCPT LQLQEPCTCT STRYEAVSIN CDGGSSLDAV LESLSNSPQA
IDSLTISNTP IEKMPGYAFQ GFQIKKLFLR NNGLRSFHPN TFTGNLENSL EELEIRGNYI
DGIPQSGVSI LKQLKILSLP DNLIEYVQDN AFLSYHSRDS LLKLDLSANN LTAIHPTGLL
GLENLSQLSL DKNLLSEIPS QALENIPSLE DLSLGVNRIH TISRNSLPLP NLKSLSLEVN
QIRLIPSDSF SETPLLSYLY LGNNLLTSID ASMFLHIGGL KVLSMSNNKD ITSIQANGKL
SVQQFKLCIC ILAFQHAPSL IRLELFDCSI SRIEPKSLQK VQHIQVILLS RNQITRISHD
TFSNLPELSE LDLSGNSINA VDDFAFSQLP MLTSLDLSSN RLESLPSNVI YDSLMQKKTS
PVQRKLSIQN NPWRCDKDLM WLRKWLRDNG DVTTAASNSP PAKCWTPSNL SGLDLRQTDS
KLPHKTTKPP VDQFQYKNQQ VTNSNGTSQL GYQNPHTEVN GLALVGLILG IVLVVFVSCI
ILGYLMRFIF LSYEAKTKPN VFGSTISSSG CIRNMYGGDG TLVSEDHGHP SSANNNVYLN
RPRHWWF
//
