ID Q93YB6_TOBAC Unreviewed; 594 AA.
AC Q93YB6;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=PBF68 protein {ECO:0000313|EMBL:CAD10638.1};
GN Name=pbf68 {ECO:0000313|EMBL:CAD10638.1};
GN Synonyms=LOC107760831 {ECO:0000313|RefSeq:XP_016434420.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|EMBL:CAD10638.1};
RN [1] {ECO:0000313|EMBL:CAD10638.1}
RP NUCLEOTIDE SEQUENCE.
RA Shen W.H.;
RT "Characterization of cDNAs encoding nucleic acid-binding proteins.";
RL Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [3] {ECO:0000313|RefSeq:XP_016434420.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the transcriptional coactivator PC4 family.
CC {ECO:0000256|ARBA:ARBA00009001}.
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DR EMBL; AJ417875; CAD10638.1; -; mRNA.
DR RefSeq; NP_001311632.1; NM_001324703.1.
DR RefSeq; XP_016434420.1; XM_016578934.1.
DR STRING; 4097.Q93YB6; -.
DR PaxDb; 4097-Q93YB6; -.
DR GeneID; 107760831; -.
DR KEGG; nta:107760831; -.
DR OMA; KNYHCWA; -.
DR OrthoDB; 26581at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003713; F:transcription coactivator activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0060261; P:positive regulation of transcription initiation by RNA polymerase II; IEA:InterPro.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 2.
DR InterPro; IPR014876; DEK_C.
DR InterPro; IPR003173; PC4_C.
DR InterPro; IPR009044; ssDNA-bd_transcriptional_reg.
DR InterPro; IPR045125; Sub1/Tcp4-like.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR13215; RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; 1.
DR PANTHER; PTHR13215:SF6; RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR KELP; 1.
DR Pfam; PF08766; DEK_C; 1.
DR Pfam; PF02229; PC4; 1.
DR Pfam; PF14223; Retrotran_gag_2; 1.
DR Pfam; PF00098; zf-CCHC; 2.
DR SMART; SM00343; ZnF_C2HC; 3.
DR SUPFAM; SSF109715; DEK C-terminal domain; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 2.
DR SUPFAM; SSF54447; ssDNA-binding transcriptional regulator domain; 1.
DR PROSITE; PS51998; DEK_C; 1.
DR PROSITE; PS50158; ZF_CCHC; 2.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 7..64
FT /note="DEK-C"
FT /evidence="ECO:0000259|PROSITE:PS51998"
FT DOMAIN 495..510
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 539..554
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT REGION 97..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 219..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 594 AA; 67507 MW; 4FA93E875A1968AE CRC64;
MEEQLPEHKR RKIREVVLDI LKTADIETAT EYSVRTTVAQ QLGTEILNIQ EKQFIRHVIE
SFLLSTVENP TLDNNRRIST AEKGVNTDFV AEEQLSADHP PTQHQEADGS LPNGNLVDSN
ENNCRTICKL SDKRSVGILD IHGKPFVAIR DFYEKDGKLV PSSRGINLSV QQWSSFRSSF
PAIVEAIATM ELKIRSTTCE NQTAADVAAQ GREQIQTNIS QSVNHQEGKL SADRNENGDD
VSNSAIITNS QVQMPIERQQ TEAGISNSAP CFAPQGQIQQ SSRTTSLAHS LVPVKTIRLD
GKNYYCWKHQ AEFFLKQLNI AYVLSEPCPN TLENRQKWVD DDYLCCHNIL NSLSDKLFEE
YSKKNYSAKE LWEELRSTYD EDFGTKSSEV NKYLQFLMVD GISILEQVQE LHKIADSLMA
SGIWIDENFH ISAIIAKLPP SWKDCRTRLM HENVPSLDML MHHLRVEDDC RNRYRNDKHE
KRVGARKKDL SKKQCYNCGK EGHISKYCTE RNYQGCEKSN GRESETIPVV TEAKINGQCY
NCGKEGHISK YCTERNYQVL ENSNGKESET IPVTEAKING QCYICGKEGH LKKL
//
