ID Q94HT9_ORYSJ Unreviewed; 1714 AA.
AC Q94HT9; Q7XG10;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 132.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN OrderedLocusNames=LOC_Os10g16720 {ECO:0000313|EMBL:AAP52863.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947 {ECO:0000313|EMBL:AAP52863.1};
RN [1] {ECO:0000313|EMBL:AAP52863.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12791992; DOI=10.1126/science.1083523;
RG Rice Chromosome 10 Sequencing Consortium;
RT "In-depth view of structure, activity, and evolution of rice chromosome
RT 10.";
RL Science 300:1566-1569(2003).
RN [2] {ECO:0000313|EMBL:AAP52863.1}
RP NUCLEOTIDE SEQUENCE.
RA Buell C.R., Wing R.A., McCombie W.R., Messing J., Yuan Q., Ouyang S.;
RL Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAP52863.1}
RP NUCLEOTIDE SEQUENCE.
RA Buell R.;
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DP000086; AAP52863.1; -; Genomic_DNA.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR005162; Retrotrans_gag_dom.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR45835:SF87; RNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR45835; YALI0A06105P; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF03732; Retrotrans_gag; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF08284; RVP_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50878; RT_POL; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 548..563
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 801..980
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 1345..1508
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 117..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 450..543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 89..116
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 140..164
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..516
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1714 AA; 194669 MW; 168C0139B37AF1E0 CRC64;
MAVEASGGTA DHACQEAAYL MMARIRERHD YIFHDTAYRY HPRRAHGDGV SSFRPTAGEN
DTTFGHMCAV IRGLDRMHSD LHKATKALND GKLMRIVALK DEIARLKKEN AQLKGLPAPG
GVRIRTTPRK TTTAPVRIQL APRNPPPPAA PAAPSVPPAV PAAPAPAPAF TLSFAPASAA
RGSASGTGGC LFGMVYTRNG SRATGEGSNG EERADGVHPN SDSGNGPPPL PENPTLAQVM
AHQTQMIAAM MQQMQQQHQQ MHQRMMQHAE QQHQQFGPPP PQSKLPEFLR VRPPTFSSTT
NPMEANDWLH AIEKKLNLLQ CNDQEKVAFA THQLQGPASA WWDNHMATRP PGTEVTWAEF
CRSFRKAQVP DGVVAQKKRE FRALHQGNRT VTEYLHEFNR LARYAPEDVR TDAEKQEKFM
AGLDDELTNQ LISGDYADFE RLVDKAIRQE DQRNKMDRKR KAAQFRAHQG SHQRPRFTPG
QQGGPTTMIV RQHRPFNPSN FHQGTSGSQN HHGSQPNRGA APRPSVAPAQ SGQPAQAKKE
TGAKPGSCFN CGELGHFADK CPKPRRAGPR FIQARVNHAS AEEAQAAPEV VLGTFPVNSI
PATVLFDSGA THSFISKKFV GMHGLIREEL STPMRVHTPG NSSTSVQFSP SITIEIQRSP
FLANLILLES KDLDVILGMD WLTKFKGVID CASRTVTLTN EKGETVVYKS LVSPKKGVSL
NQIETEIPVD TVEKNLRKLE DIPIVCEYPE VFPEDLTTMP PKREIEFRID LAPGTAPIYK
RPYRMAANEL AEVKKQVDEQ LQKGYIRPST SPWGAPVIFV EKKDKTKRMC VDYRALNEVT
IKNKYPLPRI DDLFDQLKGA KVFSKIDLRS GYHQLRIREE DIPKTAFTTR YGLYECTVMS
FGLTNAPAFF MNLMNKVFME FLDKFVVVFI DDILIYSKSE EEHEQHLRLV LEKLKEHQLY
AKFSKCDFWL TEVKFLGHVI TAQGVAVDPS NVESVTKWTP PKTVSQIRSF LGLAGYYRRF
IENFSRIARP MTQLLKKDEK FKWTAECDKS FEELKKKLVS APVLILPDPT KDFQVYCDAS
RHGLGCVLMQ EGRVVAYASR QLRPHEGNYP THDLELAAVV HALKIWRHYL IGNRCEVYTD
HKSLKYIFTQ PDLNLRQRRW LELIKDYDMS IHYHPGKANV VADALSRKSY CTALCVEGMC
EELRQEFEHL NVGIVEHGFV AALEARPTLV DQVRAAQVND SEIAELKKNM RVGKARDFHE
DEHGTIWMGE RLCVPNDKEL KDLILTEAHQ TQYSIHPGST KMYQDLKEKF WWVSMRREIA
EFVALCDVCQ RVKAEHQRPA GLLQPLQIPE WKWEEIGMDF ITGLPRTSLG HDSIWVVVDR
LTKVAHFIPV HTTYTGKRLA ELYLARIMCL HGVPKKIVSD RGSQFTSKFW QKLQEELGTR
LNFSTAYHPQ TDGQTERVNQ ILEDMLRACA LDFGGAWDKS LPYAEFSYNN SYQASLQMAP
FEALYGRKCR TPLFWDQTGE RQLFGTEVLA EAEEKVRIIR ERLRIAQSRQ KSYADNRRRE
LTFEAGDYVY LRVTPLRGVH RFQTKGKLAP RFVGPYKILE RRGEVAYQLE LPSNMIGIHD
VFHVSQLKKC LRVPEEQADS EHIDIQEDLT YVEKPVRILD TSERRTRNKV TRFCRVQWSH
HSEEEATWER EDELKAAHPH LFTSSSESRG RDSV
//
