ID Q98PQ4_MYCPU Unreviewed; 501 AA.
AC Q98PQ4;
DT 01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2001, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=CARDIOLIPIN SYNTHETASE {ECO:0000313|EMBL:CAC13838.1};
GN OrderedLocusNames=MYPU_6650 {ECO:0000313|EMBL:CAC13838.1};
OS Mycoplasmopsis pulmonis (strain UAB CTIP) (Mycoplasma pulmonis).
OC Bacteria; Mycoplasmatota; Mycoplasmoidales; Metamycoplasmataceae;
OC Mycoplasmopsis.
OX NCBI_TaxID=272635 {ECO:0000313|Proteomes:UP000000528};
RN [1] {ECO:0000313|EMBL:CAC13838.1, ECO:0000313|Proteomes:UP000000528}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAB CTIP {ECO:0000313|EMBL:CAC13838.1,
RC ECO:0000313|Proteomes:UP000000528};
RX PubMed=11353084; DOI=10.1093/nar/29.10.2145;
RA Chambaud I., Heilig R., Ferris S., Barbe V., Samson D., Galisson F.,
RA Moszer I., Dybvig K., Wroblewski H., Viari A., Rocha E.P.C., Blanchard A.;
RT "The complete genome sequence of the murine respiratory pathogen Mycoplasma
RT pulmonis.";
RL Nucleic Acids Res. 29:2145-2153(2001).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AL445565; CAC13838.1; -; Genomic_DNA.
DR PIR; A90595; A90595.
DR AlphaFoldDB; Q98PQ4; -.
DR STRING; 272635.gene:17577273; -.
DR KEGG; mpu:MYPU_6650; -.
DR eggNOG; COG1502; Bacteria.
DR HOGENOM; CLU_038053_1_2_14; -.
DR BioCyc; MPUL272635:G1GT6-674-MONOMER; -.
DR Proteomes; UP000000528; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030572; F:phosphatidyltransferase activity; IEA:UniProt.
DR GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:UniProt.
DR CDD; cd09110; PLDc_CLS_1; 1.
DR CDD; cd09112; PLDc_CLS_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR027379; CLS_N.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR Pfam; PF13396; PLDc_N; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000528};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 241..268
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 417..444
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 501 AA; 59592 MW; F7AAE8E596EC6AC9 CRC64;
MDKKNFTRFL WYFLSFLFLV INIVVFWLIF HLNYVYFSLM IAIVYLINTG VVVFIFMQNR
NSSSKLSWIV VITILPFFGH LLYFLVGQKY RHRKDYDAYY KNFNNILKDG TNIDDFSTMI
HDFGEKNLFN QLSLLSQKPI LPAKFKMFSH PYKYFNSLFE HIEKAQKEIW IVSYYAKDGE
LVDEFFSLLI KKATNGVKIK WLIDDFGQRH LKRKTLDRLK HPNIEIEFIG RLRFGFLISS
NFYRNHRKFF IIDKKIVFNG GSNISDRYIS LDSQFGYYHD INYMIKGPYV HSYIIIFIYM
WKRWRNIELR YKEPIGELEN NFESRAIIFE DGPELNDSII EDSLIKLIAN AKEEIKISTP
YFSLSNGLFN AFKIALLSGV KVSIFYPGYS AQKLVHQIGL VELKKLEKYG IKIYFTNGFF
NHSKMGIFDK NIAYIGTLNF DIRSFYAQYE TIDIVEGEVV KDIQKLFDDL EQRSVHFLKD
YQNMRSFLPK QILFKILKPL T
//
