ID Q98RW2_GUITH Unreviewed; 859 AA.
AC Q98RW2;
DT 01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2001, sequence version 1.
DT 24-JAN-2024, entry version 84.
DE RecName: Full=N-acetyltransferase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=orf859 {ECO:0000313|EMBL:AAK39838.1};
OS Guillardia theta (Cryptophyte) (Cryptomonas phi).
OG Nucleomorph {ECO:0000313|EMBL:AAK39838.1}.
OC Eukaryota; Cryptophyceae; Pyrenomonadales; Geminigeraceae; Guillardia.
OX NCBI_TaxID=55529 {ECO:0000313|EMBL:AAK39838.1, ECO:0000313|Proteomes:UP000242167};
RN [1] {ECO:0000313|EMBL:AAK39838.1, ECO:0000313|Proteomes:UP000242167}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11323671; DOI=10.1038/35074092;
RA Douglas S., Zauner S., Fraunholz M., Beaton M., Penny S., Deng L., Wu X.,
RA Reith M., Cavalier-Smith T., Maier U.;
RT "The highly reduced genome of an enslaved algal nucleus.";
RL Nature 410:1091-1096(2001).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
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DR EMBL; AF165818; AAK39838.1; -; Genomic_DNA.
DR PIR; C90088; C90088.
DR RefSeq; XP_001713543.1; XM_001713491.1.
DR AlphaFoldDB; Q98RW2; -.
DR GeneID; 857326; -.
DR Proteomes; UP000242167; Chromosome 1.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.11040; -; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR007807; Helicase_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032672; TmcA/NAT10/Kre33.
DR InterPro; IPR013562; TmcA_N.
DR InterPro; IPR027992; tRNA_bind_dom.
DR PANTHER; PTHR10925; N-ACETYLTRANSFERASE 10; 1.
DR PANTHER; PTHR10925:SF5; RNA CYTIDINE ACETYLTRANSFERASE; 1.
DR Pfam; PF13718; GNAT_acetyltr_2; 1.
DR Pfam; PF05127; Helicase_RecD; 1.
DR Pfam; PF08351; TmcA_N; 1.
DR Pfam; PF13725; tRNA_bind_2; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleomorph {ECO:0000313|EMBL:AAK39838.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 7..181
FT /note="tRNA(Met) cytidine acetyltransferase TmcA N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08351"
FT DOMAIN 259..452
FT /note="Helicase"
FT /evidence="ECO:0000259|Pfam:PF05127"
FT DOMAIN 493..706
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13718"
FT DOMAIN 714..857
FT /note="Possible tRNA binding"
FT /evidence="ECO:0000259|Pfam:PF13725"
SQ SEQUENCE 859 AA; 101845 MW; 37223389B17F0EEB CRC64;
MSDFYLNQLL ELSNKNSFRT IFLISGSNVL HEIAKIHYLL SKYTSKNKNN ILWVYNDHNS
FEKLKKSKKN ILVREFFENS QVRYLYYKDS KKILGNSFRI CILQDLKAIT PNIFLRIVET
IEGGGVIILI SDHLEKQKHF NLEDNYININ TKSKIYLNLL GRFIENFLYA LKNCPVFFFI
DSDYIKFDLY KSKISLLNKG IESANTSKKN LYIKLVDSIS NVQPINNLIK KTKTFDQARA
FLSLTESIAD KNKYSRIIMT SGRGRGKSSV LGLACCSAIA YGFSNIFITS TTVENVNTFY
AFLILGLETI GLKENKDFEI IFNKRKKCIH KVNIFNTHKQ FIKFVKPEEI NEKKDFIELL
IIEESATFQF EILKTFTGPF ITIFSTTYEG YEGSGRSFNV KFLDWIKKDI NLENKTRYIN
KIIYYKEIIL SEPIRYSTDD YLEKWINDYF FFKELFPLNT LNLCPDPFSC KLYLVDRNSL
FSNHKLSRKI LHKIVNIFFF SHYKNSPDDL QLMCDSPFHR IFVLIHQKDI SLSLIPDILA
AVQISYEGQI SKNYAEKKFQ YQFSENGDLI PWIISKYYFN FNFAELSGIR IVRIGVHSGI
QNLGFGSRII QQLEEFCKKK HAHNYEVNKF YSKHSQEKKI VQFYPSLFID LKSRITPEVD
YIGVSFNLNS RLFFFWNKNK FKTILIKKNR DLYFTKYSFI MIRDLKVNKI NINWFLNIQK
KFVRNFVNLI DTEFKDLELK VIFYMINDFL INRYKDKSFC FFNNQLLSYY ELKKIKMFIT
KKNLDFDYIG YIFKKISKIL LFKNLTVNKL KISEILILIG LGMQKKKINS ISRELEMRKD
HIFLLIHKIL KKFLIYVNY
//
