ID Q98SI5_SQUCE Unreviewed; 49 AA.
AC Q98SI5;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Metallothionein {ECO:0000256|RuleBase:RU000621};
DE Flags: Fragment;
GN Name=MT {ECO:0000313|EMBL:AAK31301.1};
OS Squalius cephalus (Chub) (Leuciscus cephalus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Leuciscidae; Leuciscinae; Squalius.
OX NCBI_TaxID=8284 {ECO:0000313|EMBL:AAK31301.1};
RN [1] {ECO:0000313|EMBL:AAK31301.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Liver {ECO:0000313|EMBL:AAK31301.1};
RX PubMed=15178096; DOI=10.1016/j.marenvres.2004.03.059;
RA Hayes R.A., Regondi S., Winter M.J., Butler P.J., Agradi E., Taylor E.W.,
RA Chipman J.K.;
RT "Cloning of a chub metallothionein cDNA and development of competitive RT-
RT PCR of chub metallothionein mRNA as a potential biomarker of heavy metal
RT exposure.";
RL Mar. Environ. Res. 58:665-669(2004).
CC -!- FUNCTION: Metallothioneins have a high content of cysteine residues
CC that bind various heavy metals. {ECO:0000256|ARBA:ARBA00002568,
CC ECO:0000256|RuleBase:RU000621}.
CC -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 1 family.
CC {ECO:0000256|ARBA:ARBA00007283, ECO:0000256|RuleBase:RU000621}.
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DR EMBL; AY029370; AAK31301.1; -; mRNA.
DR AlphaFoldDB; Q98SI5; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 4.10.10.10; Metallothionein Isoform II; 1.
DR InterPro; IPR017854; Metalthion_dom_sf.
DR InterPro; IPR023587; Metalthion_dom_sf_vert.
DR InterPro; IPR000006; Metalthion_vert.
DR InterPro; IPR018064; Metalthion_vert_metal_BS.
DR PANTHER; PTHR23299; METALLOTHIONEIN; 1.
DR PANTHER; PTHR23299:SF18; METALLOTHIONEIN-3; 1.
DR Pfam; PF00131; Metallothio; 1.
DR SUPFAM; SSF57868; Metallothionein; 1.
DR PROSITE; PS00203; METALLOTHIONEIN_VRT; 1.
PE 2: Evidence at transcript level;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000621};
KW Metal-thiolate cluster {ECO:0000256|ARBA:ARBA00022851,
KW ECO:0000256|RuleBase:RU000621}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAK31301.1"
FT NON_TER 49
FT /evidence="ECO:0000313|EMBL:AAK31301.1"
SQ SEQUENCE 49 AA; 4803 MW; AFCDC7534D883CBA CRC64;
AKTGTCNCGA TCKCTNCQCT TCKKSCCTCC PSGCSKCASG CVCKGNSCG
//
