ID Q99PT2_CAVPO Unreviewed; 50 AA.
AC Q99PT2;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=Prostaglandin H synthase 1 {ECO:0000313|EMBL:BAB21394.1};
DE Flags: Fragment;
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|EMBL:BAB21394.1};
RN [1] {ECO:0000313|EMBL:BAB21394.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Lung {ECO:0000313|EMBL:BAB21394.1};
RA Oguma T., Asano K., Shiomi T., Fukunaga K., Nakamura M., Matsubara H.,
RA Lilly C.M., Drazen J.M., Yamaguchi K.;
RT "Cyclooxygenase-2 expression during allergic inflammation in guinea pig
RT lungs.";
RL Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004406}. Microsome membrane
CC {ECO:0000256|ARBA:ARBA00004174}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004174}.
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DR EMBL; AB054840; BAB21394.1; -; mRNA.
DR AlphaFoldDB; Q99PT2; -.
DR HOGENOM; CLU_022428_0_0_1; -.
DR UniPathway; UPA00662; -.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR GO; GO:0004666; F:prostaglandin-endoperoxide synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR InterPro; IPR019791; Haem_peroxidase_animal.
DR InterPro; IPR010255; Haem_peroxidase_sf.
DR InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR PANTHER; PTHR11903; PROSTAGLANDIN G/H SYNTHASE; 1.
DR PANTHER; PTHR11903:SF6; PROSTAGLANDIN G_H SYNTHASE 1; 1.
DR Pfam; PF03098; An_peroxidase; 1.
DR SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR PROSITE; PS50292; PEROXIDASE_3; 1.
PE 2: Evidence at transcript level;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAB21394.1"
FT NON_TER 50
FT /evidence="ECO:0000313|EMBL:BAB21394.1"
SQ SEQUENCE 50 AA; 5759 MW; 1E7FCB0FFC4040D5 CRC64;
RKRFGMKPYT SFQELTGDKE MAAELEELYG DIDALEFYPG LLLEKCLPNS
//
