ID SUCC_CAUCR Reviewed; 399 AA.
AC Q9AB94;
DT 27-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 01-MAY-2013, entry version 82.
DE RecName: Full=Succinyl-CoA ligase [ADP-forming] subunit beta;
DE EC=6.2.1.5;
DE AltName: Full=Succinyl-CoA synthetase subunit beta;
DE Short=SCS-beta;
GN Name=sucC; OrderedLocusNames=CC_0337;
OS Caulobacter crescentus (strain ATCC 19089 / CB15).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=190650;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15;
RX PubMed=11259647; DOI=10.1073/pnas.061029298;
RA Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H.,
RA Kolonay J.F., Smit J., Craven M.B., Khouri H.M., Shetty J.,
RA Berry K.J., Utterback T.R., Tran K., Wolf A.M., Vamathevan J.J.,
RA Ermolaeva M.D., White O., Salzberg S.L., Venter J.C., Shapiro L.,
RA Fraser C.M.;
RT "Complete genome sequence of Caulobacter crescentus.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC -!- CATALYTIC ACTIVITY: ATP + succinate + CoA = ADP + phosphate +
CC succinyl-CoA.
CC -!- COFACTOR: Binds 1 magnesium or manganese ion per subunit (By
CC similarity).
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC succinate from succinyl-CoA (ligase route): step 1/1.
CC -!- SUBUNIT: Heterotetramer of two alpha and two beta subunits (By
CC similarity).
CC -!- SIMILARITY: Belongs to the succinate/malate CoA ligase beta
CC subunit family.
CC -!- SIMILARITY: Contains 1 ATP-grasp domain.
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DR EMBL; AE005673; AAK22324.1; -; Genomic_DNA.
DR PIR; H87290; H87290.
DR RefSeq; NP_419156.1; NC_002696.2.
DR ProteinModelPortal; Q9AB94; -.
DR SMR; Q9AB94; 1-397.
DR EnsemblBacteria; AAK22324; AAK22324; CC_0337.
DR GeneID; 942248; -.
DR KEGG; ccr:CC_0337; -.
DR PATRIC; 21297600; VBICauCre124313_0338.
DR eggNOG; COG0045; -.
DR HOGENOM; HOG000007059; -.
DR KO; K01903; -.
DR OMA; QPVTKIL; -.
DR ProtClustDB; PRK00696; -.
DR UniPathway; UPA00223; UER00999.
DR GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR GO; GO:0030145; F:manganese ion binding; IEA:HAMAP.
DR GO; GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:HAMAP.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:HAMAP.
DR Gene3D; 3.30.1490.20; -; 1.
DR Gene3D; 3.30.470.20; -; 1.
DR Gene3D; 3.40.50.261; -; 1.
DR HAMAP; MF_00558; Succ_CoA_beta; 1; -.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013650; ATP-grasp_succ-CoA_synth-type.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR013816; ATP_grasp_subdomain_2.
DR InterPro; IPR005811; CoA_ligase.
DR InterPro; IPR017866; Succ-CoA_synthase_bsu_CS.
DR InterPro; IPR005809; Succ_CoA_synthase_bsu.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR11815; PTHR11815; 1.
DR Pfam; PF08442; ATP-grasp_2; 1.
DR Pfam; PF00549; Ligase_CoA; 1.
DR PIRSF; PIRSF001554; SucCS_beta; 1.
DR SUPFAM; SSF52210; CoA_ligase; 1.
DR TIGRFAMs; TIGR01016; sucCoAbeta; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS01217; SUCCINYL_COA_LIG_3; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Ligase; Magnesium; Manganese;
KW Metal-binding; Nucleotide-binding; Reference proteome;
KW Tricarboxylic acid cycle.
FT CHAIN 1 399 Succinyl-CoA ligase [ADP-forming] subunit
FT beta.
FT /FTId=PRO_0000102823.
FT DOMAIN 9 254 ATP-grasp.
FT NP_BIND 35 118 ATP (By similarity).
FT METAL 207 207 Magnesium or manganese (By similarity).
FT METAL 209 209 Magnesium or manganese (By similarity).
SQ SEQUENCE 399 AA; 42037 MW; 3A20681437BEC548 CRC64;
MNIHEHQAKA VLAEFGAPVP RGFAAFTPDE AAAAAEKLGG PVFVVKSQIH AGGRGKGKFE
GLGPDAKGGV RVVKSVEEVR SNAEEMLGRV LVTHQTGPKG KQVNRLYIEE GAAIAKEFYL
SLLVDRASSK VSVVASTEGG MDIEDVAHST PEKIHTFTID PATGVWPTHH RALAKALGLT
GGLAKEAASL LNQLYTAFMA KDMAMLEINP LIVTADDHLR VLDAKLSFDG NSLFRHPDIK
ALRDESEEDP KEIEASKYDL AYIALDGEIG CMVNGAGLAM ATMDIIKLYG AEPANFLDVG
GGASKEKVTA AFKIITADPA VKGILVNIFG GIMRCDIIAE GVIAAVKEVG LQVPLVVRLE
GTNVELGKKI ISESGLNVIA ANDLSDGAEK IVAAVKGAR
//
