ID   Q9ACN2_STRPY            Unreviewed;       306 AA.
AC   Q9ACN2;
DT   01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2001, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   SubName: Full=SclB protein {ECO:0000313|EMBL:CAC33778.1};
GN   Name=sclB {ECO:0000313|EMBL:CAC33778.1};
OS   Streptococcus pyogenes.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1314 {ECO:0000313|EMBL:CAC33778.1};
RN   [1] {ECO:0000313|EMBL:CAC33778.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=655 {ECO:0000313|EMBL:CAC33778.1};
RX   PubMed=11158359;
RA   Whatmore A.M.;
RT   "Streptococcus pyogenes sclB encodes a putative hypervariable surface
RT   protein with a collagen-like repetitive structure.";
RL   Microbiology 147:419-429(2001).
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DR   EMBL; AJ301809; CAC33778.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9ACN2; -.
DR   Gene3D; 6.10.250.2770; -; 1.
DR   InterPro; IPR008160; Collagen.
DR   InterPro; IPR019931; LPXTG_anchor.
DR   InterPro; IPR019950; M_anchor.
DR   NCBIfam; NF038329; gly_rich_SclB; 1.
DR   NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR   PANTHER; PTHR24637; COLLAGEN; 1.
DR   PANTHER; PTHR24637:SF428; SCAVENGER RECEPTOR CLASS A MEMBER 3; 1.
DR   Pfam; PF01391; Collagen; 2.
DR   Pfam; PF00746; Gram_pos_anchor; 1.
DR   PRINTS; PR00015; GPOSANCHOR.
PE   4: Predicted;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW   Secreted {ECO:0000256|ARBA:ARBA00022512}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..34
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           35..306
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5039052867"
FT   DOMAIN          257..295
FT                   /note="Gram-positive cocci surface proteins LPxTG"
FT                   /evidence="ECO:0000259|Pfam:PF00746"
FT   REGION          112..266
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        196..213
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        214..250
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   306 AA;  31833 MW;  57EBDC244DF17600 CRC64;
     MNKTKQNKTK HSLLCRYGLT SAAALLLTFG GASAVKADGE DAQKRAQIQK REELLSALID
     GTSRLENKQC PYPGSTGLDD TYMNSLIQYL QERKQIEDKW RASLLKGIQD HVLDGQDGDR
     GEAGPAGPRG EAGKDGAKGD RGEAGPAGPR GEAGPAGPRG EAGPAGPRGE AGKDGAKGDR
     GEAGPAGKDG QPGKPAPKTP EVPQKPDTAP HTPKTPQIPG QSKDVTPAPQ NPSNRGLNKP
     QTQGGNQLAK TPAAHDTHRQ LPATGETTNP FFTAAAVAIM TTAGVVAVAK RQENNQSSFC
     YLTDGK
//