ID   Q9BZI2_HUMAN            Unreviewed;        94 AA.
AC   Q9BZI2;
DT   01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2001, sequence version 1.
DT   27-MAR-2024, entry version 90.
DE   SubName: Full=Iroquois-related homeobox transcription factor {ECO:0000313|EMBL:AAK01201.1};
DE   Flags: Fragment;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAK01201.1};
RN   [1] {ECO:0000313|EMBL:AAK01201.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=11435706;
RA   Ogura K., Matsumoto K., Kuroiwa A., Isobe T., Otoguro T., Jurecic V.,
RA   Baldini A., Matsuda Y., Ogura T.;
RT   "Cloning and chromosome mapping of human and chicken Iroquois (IRX)
RT   genes.";
RL   Cytogenet. Cell Genet. 92:320-325(2001).
CC   -!- SIMILARITY: Belongs to the TALE/IRO homeobox family.
CC       {ECO:0000256|ARBA:ARBA00008446}.
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DR   EMBL; AF319966; AAK01201.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9BZI2; -.
DR   PeptideAtlas; Q9BZI2; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   PANTHER; PTHR11211; IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX; 1.
DR   PANTHER; PTHR11211:SF11; IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-6; 1.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
PE   3: Inferred from homology;
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000313|EMBL:AAK01201.1}.
FT   DOMAIN          63..94
FT                   /note="Homeobox KN"
FT                   /evidence="ECO:0000259|Pfam:PF05920"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAK01201.1"
FT   NON_TER         94
FT                   /evidence="ECO:0000313|EMBL:AAK01201.1"
SQ   SEQUENCE   94 AA;  10657 MW;  C9B9100A4C395FAB CRC64;
     NPQYEFKEAA GSFTSSLAQP GAYYPYERTL GQYQYERYGA VELSGAGRRK NATRETTSTL
     KAWLNEHRKN PYPTKGEKIM LAIITKMTLT QVST
//