ID RCL1_ARATH Reviewed; 375 AA.
AC Q9C578;
DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 01-MAY-2013, entry version 86.
DE RecName: Full=Probable RNA 3'-terminal phosphate cyclase-like protein;
GN OrderedLocusNames=At5g22100; ORFNames=T6G21.20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K.,
RA Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S.,
RA Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M.,
RA Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R.,
RA Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J.,
RA Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M.,
RA Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M.,
RA Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P.,
RA Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C.,
RA Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N.,
RA Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J.,
RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S.,
RA Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W.,
RA Ramsperger U., Wedler H., Balke K., Wedler E., Peters S.,
RA van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R.,
RA Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W.,
RA Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H.,
RA Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis
RT thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RG The Arabidopsis Information Resource (TAIR);
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
RA Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
RA Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
RA Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
RA Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
RA Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
RA Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
RA Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
RA Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
RA Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
RA Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
RA Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Does not have cyclase activity. Plays a role in 40S-
CC ribosomal-subunit biogenesis in the early pre-rRNA processing
CC steps at sites A0, A1 and A2 that are required for proper
CC maturation of the 18S RNA (By similarity).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus (By similarity).
CC -!- SIMILARITY: Belongs to the RNA 3'-terminal cyclase family. Type 2
CC subfamily.
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DR EMBL; AL589883; CAC34503.1; -; Genomic_DNA.
DR EMBL; CP002688; AED92983.1; -; Genomic_DNA.
DR EMBL; BT002059; AAN72070.1; -; mRNA.
DR IPI; IPI00532522; -.
DR RefSeq; NP_680196.1; NM_147891.3.
DR UniGene; At.44338; -.
DR UniGene; At.45633; -.
DR ProteinModelPortal; Q9C578; -.
DR SMR; Q9C578; 8-369.
DR STRING; 3702.AT5G22100.1-P; -.
DR PaxDb; Q9C578; -.
DR PRIDE; Q9C578; -.
DR EnsemblPlants; AT5G22100.1; AT5G22100.1; AT5G22100.
DR GeneID; 832271; -.
DR KEGG; ath:AT5G22100; -.
DR TAIR; At5g22100; -.
DR eggNOG; COG0430; -.
DR HOGENOM; HOG000157670; -.
DR InParanoid; Q9C578; -.
DR KO; K11108; -.
DR OMA; FMKHPLR; -.
DR PhylomeDB; Q9C578; -.
DR ProtClustDB; CLSN2690185; -.
DR Genevestigator; Q9C578; -.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR Gene3D; 3.65.10.20; -; 2.
DR InterPro; IPR013791; RNA3'-term_phos_cycl_insert.
DR InterPro; IPR023797; RNA3'_phos_cyclase_dom.
DR InterPro; IPR000228; RNA3'_term_phos_cyc.
DR InterPro; IPR016443; RNA3'_term_phos_cyc_type_2.
DR InterPro; IPR020719; RNA3'_term_phos_cycl-like_CS.
DR InterPro; IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b.
DR PANTHER; PTHR11096; PTHR11096; 1.
DR Pfam; PF01137; RTC; 1.
DR Pfam; PF05189; RTC_insert; 1.
DR PIRSF; PIRSF005378; RNA3'_term_phos_cycl_euk; 1.
DR SUPFAM; SSF55205; RNA3'_cycl/enolpyr_transf_A/B; 1.
DR TIGRFAMs; TIGR03400; 18S_RNA_Rcl1p; 1.
DR PROSITE; PS01287; RTC; 1.
PE 2: Evidence at transcript level;
KW Complete proteome; Nucleus; Reference proteome; Ribosome biogenesis.
FT CHAIN 1 375 Probable RNA 3'-terminal phosphate
FT cyclase-like protein.
FT /FTId=PRO_0000156442.
SQ SEQUENCE 375 AA; 40874 MW; 3C7D286D4386D5AF CRC64;
MVMMKKMKGS QSFRQRLLLS TLSSTPISID EIRADETIPG LRPHEVNLLR LLEIVTDDAV
VDINETGTRL KYKPGTIVGG KNLVHSCSLS RSIGYYLEPL LLLGLFGKKP LSIRLKGITN
DPRDASVDTF RSTTLNIIKR FGVPAEDLEL KIEARGVAPN GGGEVLLTVP NIKTLSAVHW
VEEGMVKKIR GTTFSTRVTS DFEHSMRFAA RGIFNNLLPD VHIFQDHRAG AQAGKSPGYG
ISLAAETTTG CFISADTTVS CERPDETGEL DVEKKERSPA EDTGVEVASW LLQEIEKGGV
VDSTHQGLLF LLCALSEQDV SKVRVGTLSP YAVETLRNIK EFLGVKFAIK PDPLTGTVIL
KCTGSGLINL SRKLS
//
