ID Q9CD64_MYCLE Unreviewed; 353 AA.
AC Q9CD64;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE RecName: Full=Acetyltransferase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=ML0187 {ECO:0000313|EMBL:CAC29695.1};
OS Mycobacterium leprae (strain TN).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=272631 {ECO:0000313|EMBL:CAC29695.1, ECO:0000313|Proteomes:UP000000806};
RN [1] {ECO:0000313|EMBL:CAC29695.1, ECO:0000313|Proteomes:UP000000806}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TN {ECO:0000313|EMBL:CAC29695.1,
RC ECO:0000313|Proteomes:UP000000806};
RX PubMed=11234002; DOI=10.1038/35059006;
RA Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA Barrell B.G.;
RT "Massive gene decay in the leprosy bacillus.";
RL Nature 409:1007-1011(2001).
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DR EMBL; AL583917; CAC29695.1; -; Genomic_DNA.
DR PIR; C86932; C86932.
DR RefSeq; NP_301261.1; NC_002677.1.
DR AlphaFoldDB; Q9CD64; -.
DR STRING; 272631.gene:17574003; -.
DR KEGG; mle:ML0187; -.
DR PATRIC; fig|272631.5.peg.293; -.
DR Leproma; ML0187; -.
DR eggNOG; COG0664; Bacteria.
DR eggNOG; COG1670; Bacteria.
DR HOGENOM; CLU_836314_0_0_11; -.
DR OrthoDB; 190266at2; -.
DR Proteomes; UP000000806; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0097159; F:organic cyclic compound binding; IEA:UniProt.
DR CDD; cd00038; CAP_ED; 1.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR24567:SF80; CRP-LIKE CAMP-ACTIVATED GLOBAL TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF13302; Acetyltransf_3; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51186; GNAT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000806}.
FT DOMAIN 40..142
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 176..338
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 353 AA; 38407 MW; 966BE33620D0A18D CRC64;
MAGSWQCGHC ESCASPLGPR DIAVVELIAD RAEEFAAMDI FRGLPAEDLM SVAVSVEPVL
AAAGEVLMQQ GEQAVSFLLI SSGNVEVRRV DDDGAVIVGQ ASHGMIIGEI ALLRDGRRTA
TVITTEPLTG WVGDIDAFAQ MVQIPSITRR LLLTVRQRLA AFITPIPVQL RDGTHLMLRP
VLPGDTERSL RGHVRFSRET LYLRFMSARA PSDELMHYLS EVDYVDHFVW VVTDGGDPVA
DARFVRDESD PTLAEIAFTV ADAYQGRGVG NFLISALSIA AHVNGVNRFS ARMLTDNGPM
RAIMDHHGAV WRRYDVGVIT TVIDVPRQRD LIIGRAMADQ IAGVVRQVIG AVG
//
