ID Q9CD95_MYCLE Unreviewed; 411 AA.
AC Q9CD95;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Probable hydrolase {ECO:0000313|EMBL:CAC29627.1};
GN Name=lipE {ECO:0000313|EMBL:CAC29627.1};
GN OrderedLocusNames=ML0119 {ECO:0000313|EMBL:CAC29627.1};
OS Mycobacterium leprae (strain TN).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=272631 {ECO:0000313|EMBL:CAC29627.1, ECO:0000313|Proteomes:UP000000806};
RN [1] {ECO:0000313|EMBL:CAC29627.1, ECO:0000313|Proteomes:UP000000806}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TN {ECO:0000313|EMBL:CAC29627.1,
RC ECO:0000313|Proteomes:UP000000806};
RX PubMed=11234002; DOI=10.1038/35059006;
RA Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA Barrell B.G.;
RT "Massive gene decay in the leprosy bacillus.";
RL Nature 409:1007-1011(2001).
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DR EMBL; AL583917; CAC29627.1; -; Genomic_DNA.
DR PIR; G86923; G86923.
DR RefSeq; NP_301215.1; NC_002677.1.
DR RefSeq; WP_010907540.1; NC_002677.1.
DR AlphaFoldDB; Q9CD95; -.
DR STRING; 272631.gene:17573932; -.
DR KEGG; mle:ML0119; -.
DR PATRIC; fig|272631.5.peg.183; -.
DR Leproma; ML0119; -.
DR eggNOG; COG1680; Bacteria.
DR HOGENOM; CLU_035614_3_0_11; -.
DR OrthoDB; 9809635at2; -.
DR Proteomes; UP000000806; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR001466; Beta-lactam-related.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR NCBIfam; NF038269; lipase_LipE; 1.
DR PANTHER; PTHR43283; BETA-LACTAMASE-RELATED; 1.
DR PANTHER; PTHR43283:SF3; BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00144; Beta-lactamase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CAC29627.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000806}.
FT DOMAIN 42..393
FT /note="Beta-lactamase-related"
FT /evidence="ECO:0000259|Pfam:PF00144"
SQ SEQUENCE 411 AA; 44963 MW; 9ED2E2C5320DF210 CRC64;
MTSDGKIRVP TDLDAVTAIG DEDHSDIDSA AVERIWQATR HWYQAGMHPA IQLCIRQHGR
VVLNRAIGHG WGNAPTDPHD AEKIPVTTDT PFCAYSAAKA ITATVVHMLV ERGHFSLDDR
VCEYLPTYTS YGKHRTTIRH VLTHSAGVPF PTGPRPDVTR ADDHAYAQQK LSELRPFYRP
GLVHIYHALT WGPLMREIIW TATGKEIRDI LAAEILDPLG FRWTNFGVAE EDVPLVALSH
ATGRPLPPII AAIFRKAIGG TVHEVIPYTN TPPFLTTIVP SSNTVSTANE LSRFAEIWLR
GGELDGIRVL RSETLLGAVA ECRRLRPDFV VGLMPARWGT GFILGTNKFG PFGRNAPAAF
GHLGLVNIAI WADPQRSMAA GLISSGKPGQ DPNAGRYGAL MNTITAEIPV H
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