ID Q9DDF6_PETMA Unreviewed; 247 AA.
AC Q9DDF6;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 24-JAN-2024, entry version 105.
DE SubName: Full=Homeodomain protein DlxD {ECO:0000313|EMBL:AAG41498.1};
GN Name=DlxD {ECO:0000313|EMBL:AAG41498.1};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|EMBL:AAG41498.1};
RN [1] {ECO:0000313|EMBL:AAG41498.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11172008; DOI=10.1073/pnas.98.4.1665;
RA Neidert A.H., Virupannavar V., Hooker G.W., Langeland J.A.;
RT "Lamprey Dlx genes and early vertebrate evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:1665-1670(2001).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the distal-less homeobox family.
CC {ECO:0000256|ARBA:ARBA00007916}.
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DR EMBL; AY010119; AAG41498.1; -; mRNA.
DR AlphaFoldDB; Q9DDF6; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR InterPro; IPR000047; HTH_motif.
DR PANTHER; PTHR24327; HOMEOBOX PROTEIN; 1.
DR PANTHER; PTHR24327:SF33; HOMEOBOX PROTEIN DLX-1; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}.
FT DOMAIN 114..174
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 116..175
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
SQ SEQUENCE 247 AA; 26320 MW; 5A3FD6BEBCF10AE8 CRC64;
MMSASTAATS MAHHTHHYPS HCLPSAGHDS SYAAAAAAAA AAAAASSYQS RPLGYPYLNP
IGSGTGGASG GYSLGALPSY QPSSALNQTR LDDTDPEKTP VIHNGELRFN GKGKKIRKPR
TIYSSLQLQA LNRRFQQTQY LALPERAELA ASLGLTQTQV KIWFQNKRSK YKKLMKAGGA
GLENNPLVNT GCLPPSPVSG HPQQAVWDMG PPAVKGTVMS PGAYMPPYSH WYSPSAHQES
MANQPVM
//
