ID Q9HFA2_ROSNE Unreviewed; 353 AA.
AC Q9HFA2;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=G protein alpha subunit {ECO:0000313|EMBL:BAB20820.1};
DE SubName: Full=Putative guanine nucleotide-binding protein subunit alpha {ECO:0000313|EMBL:GAP87803.1};
GN Name=WGA2 {ECO:0000313|EMBL:BAB20820.1};
GN ORFNames=SAMD00023353_2801440 {ECO:0000313|EMBL:GAP87803.1};
OS Rosellinia necatrix (White root-rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Xylariaceae; Rosellinia.
OX NCBI_TaxID=77044 {ECO:0000313|EMBL:BAB20820.1};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=W8 {ECO:0000313|EMBL:BAB20820.1};
RX PubMed=11330689; DOI=10.1271/bbb.65.678;
RA Aimi T., Kano S., Wang Q., Morinaga T.;
RT "Molecular cloning of three genes encoding G protein alpha subunits in the
RT white root rot fungus, Rosellinia necatrix.";
RL Biosci. Biotechnol. Biochem. 65:678-682(2001).
RN [2] {ECO:0000313|EMBL:GAP87803.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W97 {ECO:0000313|EMBL:GAP87803.1};
RA Kanematsu S.;
RT "Draft genome sequence of Rosellinia necatrix.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma. The
CC alpha chain contains the guanine nucleotide binding site.
CC {ECO:0000256|ARBA:ARBA00011356}.
CC -!- SIMILARITY: Belongs to the G-alpha family. G(q) subfamily.
CC {ECO:0000256|ARBA:ARBA00007976}.
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DR EMBL; AB045578; BAB20820.1; -; Genomic_DNA.
DR EMBL; DF977473; GAP87803.1; -; Genomic_DNA.
DR PIR; JC7661; JC7661.
DR AlphaFoldDB; Q9HFA2; -.
DR STRING; 77044.Q9HFA2; -.
DR OMA; QVIWADA; -.
DR OrthoDB; 2897309at2759; -.
DR Proteomes; UP000054516; Unassembled WGS sequence.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IEA:InterPro.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IEA:InterPro.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002975; Fungi_Gprotein_alpha.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF355; GUANINE NUCLEOTIDE-BINDING PROTEIN G(O) SUBUNIT ALPHA; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR01241; GPROTEINAFNG.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054516};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
SQ SEQUENCE 353 AA; 41016 MW; 0EB84C4B292B70E6 CRC64;
MGCGMSTEEK EGKARNEEIE NQLKRDKMMQ RNEIKMLLLG AGESGKSTIL KQMKLIHEGG
YSRDERESFK EIIFSNTVQS MRVILEAMES LELPLEEPRM EYHVQTIFMQ PAQIEGDVLP
PEVGGAIEAL WKDHGVQECF KRSREYQLND SARYYFDNIV RIATPDYMPN DQDVLRSRVK
TTGITETTFI IGDLTYRMFD VGGQRSERKK WIHCFENVTT ILFLVAISEY DQLLFEDETV
NRMQEALTLF DSICNSRWFI KTSIILFLNK IDRFKEKLPV SPMKNYFPDY EGGDDYAAAC
DYILNRFVSL NQHETKQIYT HFTCATDTTQ IRFVMAAVND IIIQENLRLC GLI
//
